Sarcopenia Clinical Trial
Official title:
Evaluation Of Sarcopenia By Adding Anthropometric Measurements To The SARC-F Questionnaire
NCT number | NCT05241886 |
Other study ID # | Sarcopenia001 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | July 1, 2018 |
Est. completion date | May 30, 2019 |
Verified date | February 2022 |
Source | Ege University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The aim of this study is to examine the performance of determining the sarcopenia by anthropometric measurements (mid-upper arm circumference and calf circumference) added to the SARC-F questionnaire developed as a screening tool for the risk of sarcopenia in the community-dwelling older adults. The risk of sarcopenia of the individuals over 65 years of age who applied to the Geriatrics Department of Ege University Medical Faculty Hospital Internal Diseases Department. was determined by the SARC-F questionnaire, muscle mass was established by bioelectrical impedance analysis, muscle strength was assessed by handgrip strength, physical performance was assessed by a 4-meter walking test and presence of malnutrition was assessed with an MNA-long form. For the diagnosis of sarcopenia; old (EWGSOP 1) and revised (EWGSOP 2) diagnostic criteria of Sarcopenia Study Group in Elderly Individuals of the European Union Geriatric Medicine Association were used. New parameters were obtained by adding calf circumference (SARC-CC) and mid-upper arm circumference (SARC-MUAC) measurements were added separately and together (SARC-CC-MUAC) to the SARC-F. For the calf circumference cut-off points of <31 cm and <33 cm and for the mid-upper arm circumference cut-off points of <25 cm and <31 cm were used for the sensitivity and specificity analyses.
Status | Completed |
Enrollment | 190 |
Est. completion date | May 30, 2019 |
Est. primary completion date | March 2, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 65 Years and older |
Eligibility | Inclusion Criteria: participants who applied to the geriatrics outpatient clinic for any reason Exclusion Criteria: Participants with an implanted pacemaker, severe mental illness, unable to walk, severe heart failure, severe renal failure, clinically visible edema, and unable to communicate. |
Country | Name | City | State |
---|---|---|---|
Turkey | Ege University | Izmir | Bornova |
Lead Sponsor | Collaborator |
---|---|
Ege University |
Turkey,
Abd-El-Gawad WM, Abou-Hashem RM, El Maraghy MO, Amin GE. The validity of Geriatric Nutrition Risk Index: simple tool for prediction of nutritional-related complication of hospitalized elderly patients. Comparison with Mini Nutritional Assessment. Clin Nutr. 2014 Dec;33(6):1108-16. doi: 10.1016/j.clnu.2013.12.005. Epub 2013 Dec 28. — View Citation
Ates Bulut E, Soysal P, Dokuzlar O, Kocyigit SE, Aydin AE, Yavuz I, Isik AT. Validation of population-based cutoffs for low muscle mass and strength in a population of Turkish elderly adults. Aging Clin Exp Res. 2020 Sep;32(9):1749-1755. doi: 10.1007/s40520-019-01448-4. Epub 2020 Jan 2. — View Citation
Bahat G, Yilmaz O, Kiliç C, Oren MM, Karan MA. Performance of SARC-F in Regard to Sarcopenia Definitions, Muscle Mass and Functional Measures. J Nutr Health Aging. 2018;22(8):898-903. doi: 10.1007/s12603-018-1067-8. — View Citation
da Luz MCL, Pinho CPS, Bezerra GKA, da Conceição Chaves de Lemos M, da Silva Diniz A, Cabral PC. SARC-F and SARC-CalF in screening for sarcopenia in older adults with Parkinson's disease. Exp Gerontol. 2021 Feb;144:111183. doi: 10.1016/j.exger.2020.111183. Epub 2020 Dec 3. — View Citation
Drey M, Ferrari U, Schraml M, Kemmler W, Schoene D, Franke A, Freiberger E, Kob R, Sieber C. German Version of SARC-F: Translation, Adaption, and Validation. J Am Med Dir Assoc. 2020 Jun;21(6):747-751.e1. doi: 10.1016/j.jamda.2019.12.011. Epub 2020 Jan 21. — View Citation
Fu X, Tian Z, Thapa S, Sun H, Wen S, Xiong H, Yu S. Comparing SARC-F with SARC-CalF for screening sarcopenia in advanced cancer patients. Clin Nutr. 2020 Nov;39(11):3337-3345. doi: 10.1016/j.clnu.2020.02.020. Epub 2020 Feb 22. — View Citation
Hajaoui M, Locquet M, Beaudart C, Reginster JY, Petermans J, Bruyère O. Sarcopenia: Performance of the SARC-F Questionnaire According to the European Consensus Criteria, EWGSOP1 and EWGSOP2. J Am Med Dir Assoc. 2019 Sep;20(9):1182-1183. doi: 10.1016/j.jamda.2019.05.021. — View Citation
Sergi G, De Rui M, Veronese N, Bolzetta F, Berton L, Carraro S, Bano G, Coin A, Manzato E, Perissinotto E. Assessing appendicular skeletal muscle mass with bioelectrical impedance analysis in free-living Caucasian older adults. Clin Nutr. 2015 Aug;34(4):667-73. doi: 10.1016/j.clnu.2014.07.010. Epub 2014 Jul 24. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | sarcopenia prevalance | number | Day 1 | |
Primary | SARC-F score | number | Day 1 | |
Primary | mid-upper arm circumference | cm | Day 1 | |
Primary | calf circumference | cm | Day 1 | |
Primary | Appendicular skeletal muscle mass index | kg/m2 | Day 1 |
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