Sarcopenia Clinical Trial
Official title:
Impact of Neuromuscular Electrical Stimulation on Physical Function in Older Adults
The purpose of this placebo controlled clinical trial is to examine the effects of of
neuromuscular electrical stimulation (NMES) training on physical activity, muscle function,
self-efficacy, and blood markers [e.g., brain-derived neurotrophic factor (BDNF)] in older
adults.
It is hypothesized that 4-weeks of NMES will increase 1) physical activity, 2) muscle
function, 3) self-efficacy, and 4) BDNF in older adults.
Sarcopenia is a destructive progressive cycle of impaired physical function resulting in loss
of muscle mass, strength, and self-confidence in ability to perform physical activities,
compounded by difficulty walking and ultimately reduced physical activity levels for many
older adults. Neuromuscular electrical stimulation (NMES) is a common therapeutic modality
used to create involuntary muscle contractions as a means to increase muscle strength, and
may be an effective treatment for improving muscle function and physical activity levels in
older adults with sarcopenia. Thus, it is critical to explore viable and effective
alternative therapies to increase physical activity. The goal of the investigators' is to
determine the effectiveness of neuromuscular electrical stimulation (NMES) at increasing
physical activity and related biological, psychological, and muscle function factors. This
placebo controlled clinical trial will use a pre-test - post-test randomized experimental
design.
Older healthy adults (60 and older) will participate in this study. Participants will undergo 4 weeks of neuromuscular electrical stimulation (NMES) training. Participants will be randomized into the one of two groups 1) NMES-millicurrent or 2) NMES microcurrent. Participants will undergo pre- and post-training testing for muscle function, physical function, and psychological variables related to physical activity. Blood samples will also be obtained pre- and post-training. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT06287502 -
Efficacy of Structured Exercise-Nutritional Intervention on Sarcopenia in Patients With Osteoporosis
|
N/A | |
| Recruiting |
NCT05063279 -
RELIEF - Resistance Training for Life
|
N/A | |
| Completed |
NCT03644030 -
Phase Angle, Lean Body Mass Index and Tissue Edema and Immediate Outcome of Cardiac Surgery Patients
|
||
| Recruiting |
NCT06143592 -
Inspiratory Muscle Training on Balance, Falls and Diaphragm Thickness in the Elderly
|
N/A | |
| Terminated |
NCT04350762 -
Nutritional Supplementation in the Elderly With Weight Loss
|
N/A | |
| Enrolling by invitation |
NCT05953116 -
Managing the Nutritional Needs of Older Filipino With Due Attention to Protein Nutrition and Functional Health Study
|
N/A | |
| Recruiting |
NCT04028206 -
Resistance Exercise or Vibration With HMB for Sarcopenia
|
N/A | |
| Enrolling by invitation |
NCT03297632 -
Improving Muscle Strength, Mass and Physical Function in Older Adults
|
N/A | |
| Completed |
NCT04015479 -
Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Adults
|
N/A | |
| Completed |
NCT03234920 -
Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation After Liver Transplantation
|
N/A | |
| Recruiting |
NCT03998202 -
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
|
||
| Recruiting |
NCT04717869 -
Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty
|
||
| Completed |
NCT05497687 -
Strength-building Lifestyle-integrated Intervention
|
N/A | |
| Completed |
NCT03119610 -
The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity
|
Phase 1/Phase 2 | |
| Recruiting |
NCT05711095 -
The Anabolic Properties of Fortified Plant-based Protein in Older People
|
N/A | |
| Recruiting |
NCT05008770 -
Trial in Elderly With Musculoskeletal Problems Due to Underlying Sarcopenia - Faeces to Unravel Gut and Inflammation Translationally
|
||
| Not yet recruiting |
NCT05860556 -
Sustainable Eating Pattern to Limit Malnutrition in Older Adults
|
||
| Recruiting |
NCT04545268 -
Prehabilitation for Cardiac Surgery in Patients With Reduced Exercise Tolerance
|
N/A | |
| Recruiting |
NCT04522609 -
Electrostimulation of Skeletal Muscles in Patients Listed for a Heart Transplant
|
N/A | |
| Recruiting |
NCT03160326 -
The QUALITY Vets Project: Muscle Quality and Kidney Disease
|