Post - Hospital Syndrome: Profile of Functional Status by Malnutrition

Sarcopenia Clinical Trial

Official title:

Post-Hospital Syndrome: Evaluation of Functional Status in Malnourished, Geriatric Patients at Hospital Discharge

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03126500
• Other study ID #: POSTHOSP
• Status: Recruiting
• Start date: May 31, 2017
• Est. completion date: June 30, 2021

Study information

• Verified date: January 2020
• Source: Charite University, Berlin, Germany
• Contact: Kristina Norman, PD Dr.
• Phone: +4930450565139
• Email: kristina.norman[@]charite.de
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Malnutrition is common problem in hospitalized geriatrics at discharge. Malnutrition is a high risk for functional limitations, impaired muscle strength and reduced quality of life.

Description:

The majority of geriatric hospitalized patients are at high risk for malnutrition at discharge, which has negative impact on post-hospital outcomes. In a cross-sectional analysis in malnourished, geriatric patients we will evaluate frailty-status and functional status using objective and subjective methods at hospital discharge. Moreover, we will investigate the association between nutritional Status and frailty, sarcopenia, quality of life and fatigue.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: June 30, 2021
• Est. primary completion date: April 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• Age = 60 years

• Informed written consent

• Existing or risk of malnutrition

• Normal cognitive status according to Mini-Mental State Examination (MMSE = 24 points)

• Life expectancy of > 3 months according to treating doctor

Exclusion Criteria:

• Age < 60 years

• Lack of informed written consent

• No risk of malnutrition

• Low cognitive status according to Mini-Mental State Examination (MMSE < 24 points)

• Life expectancy of < 3 months according to treating doctor

Related Conditions & MeSH terms

• Malnutrition
• Sarcopenia

Locations

Country	Name	City	State
Germany	Charite University, Berlin, Germany	Berlin

Sponsors (1)

Lead Sponsor	Collaborator
Charite University, Berlin, Germany

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Functional Parameter: gait speed	gait analysis	Baseline (hospital discharge)
Secondary	Functional Parameter: timed up & go (TUG) time	timed up & go (TUG) test	Baseline (hospital discharge)
Secondary	Functional Parameter: stair climbing time	stair climbing test	Baseline (hospital discharge)
Secondary	Functional Parameter: Peak expiratory flow rate	peak flow meters scale	Baseline (hospital discharge)
Secondary	Strength Parameter: Hand grip strength	Hand grip strength measurement	Baseline (hospital discharge)
Secondary	Strength Parameter: Knee extension strength	Knee extension strength measurement	Baseline (hospital discharge)
Secondary	Index of quality of life	validated questionnaire	Baseline (hospital discharge)
Secondary	Body composition	bioelectric impedance Analysis	Baseline (hospital discharge)
Secondary	Frailty-Status	Fried criteria	Baseline (hospital discharge)