Prevalence of Sarcopenia and Its Geriatric Features

Sarcopenia Clinical Trial

Official title:

Prevalence of Sarcopenia and Its Geriatric Features

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02664376
• Other study ID #: CHUB-sarcopenia
• Status: Completed
• Phase: N/A
• First received: January 19, 2016
• Last updated: January 25, 2018
• Start date: January 1, 2016
• Est. completion date: January 18, 2018

Study information

• Verified date: January 2018
• Source: Brugmann University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The goal of this study is to determine the prevalence of sarcopenia in a geriatric hospital ward.

Sarcopenia is defined by a loss of muscle mass, loss of muscle strength and loss of muscle quality. It is a geriatric syndrome that, to this date, is not systematically tracked in clinical practice.

In order to detect sarcopenia, the investigators will use the operational definition proposed by the European Working Group (EWGSOP) involving the measure of three parameters, namely the speed of walking, the muscle strength and the measurement of the muscular mass.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 834
• Est. completion date: January 18, 2018
• Est. primary completion date: January 18, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• To be admitted in the unit 83 of the Geriatric Departement of the CHU Brugmann hospital, from 10/01/2016 till 30/03/2017.

Exclusion Criteria:

• Patients unable to consent or without representatives

• Patients unable to perform the hand- grip test, the walk test or measurement of the body components by DEXA

• Patients in severe pain

• Bedridden patients

• Patients for which a clear therapeutic abstention has been established

• Language barriere that cannot be overcome

• Patients unable to walk without the help of a third person

Related Conditions & MeSH terms

• Sarcopenia

Intervention

Other:
• Sarcopenia detection
The assessment of sarcopenia is performed according to the recommendations of the EWGSOP (European Working Group on Sarcopenia in Older people). Three measurements are made: Muscle mass measurement by dual energy X-ray absorptiometry (DEXA). Walking speed measurement Hand grip test A diagnosis of sarcopenia is established if the walking speed is inferior to 0.8 m/sec, the muscular strength is low and the muscular mass is low. Data regarding the geriatric characteristics of this sarcopenic population will be collected.

Locations

Country	Name	City	State
Belgium	CHU Brugmann	Brussels

Sponsors (1)

Lead Sponsor	Collaborator
Brugmann University Hospital

Country where clinical trial is conducted

Belgium, 

References & Publications (4)

Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, Garry PJ, Lindeman RD. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998 Apr 15;147(8):755-63. Erratum in: Am J Epidemiol 1999 Jun 15;149(12):1161. — View Citation

Cesari M, Kritchevsky SB, Newman AB, Simonsick EM, Harris TB, Penninx BW, Brach JS, Tylavsky FA, Satterfield S, Bauer DC, Rubin SM, Visser M, Pahor M; Health, Aging and Body Composition Study. Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study. J Am Geriatr Soc. 2009 Feb;57(2):251-9. doi: 10.1111/j.1532-5415.2008.02126.x. — View Citation

Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinková E, Vandewoude M, Zamboni M; European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010 Jul;39(4):412-23. doi: 10.1093/ageing/afq034. Epub 2010 Apr 13. — View Citation

Lauretani F, Russo CR, Bandinelli S, Bartali B, Cavazzini C, Di Iorio A, Corsi AM, Rantanen T, Guralnik JM, Ferrucci L. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol (1985). 2003 Nov;95(5):1851-60. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of sarcopenia	Sarcopenia detection will be performed at the end of each hospitalization stay in unit 83 of the CHU Brugmann Hospital (Geriatry Department)	From 10/01/2016 till 30/03/2017 (up to 15 months)
Secondary	Percentage of hospitalized patients unable to perform the sarcopenia detection test	Systematic retrospective review of patients hospitalised in the geriatric ward of the CHU Brugmann hospital during the length of the study, in order to determine the percentage of patients that could not, because of one of more exclusion criteria, perform the sarcopenia detection test.	From 10/01/2016 till 30/03/2017 (up to 15 months)