Human Irisin Concentration in Sarcopenia

Sarcopenia Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01874912
• Other study ID #: SO(IRISIN)
• Status: Completed
• Phase: N/A
• First received: June 3, 2013
• Last updated: June 7, 2013
• Start date: November 2009
• Est. completion date: April 2011

Study information

• Verified date: June 2013
• Source: Korea University
• Contact: n/a
• Is FDA regulated: No
• Health authority: South Korea: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Irisin has been identified as a novel myokine that drives brown-fat-like conversion of white adipose tissue. In this cross-sectional study, the researches investigated whether serum irisin levels are decreased in patients with sarcopenia compared with control subjects with normal muscle mass, and assessed the association between serum irisin levels and various metabolic parameters.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 406
• Est. completion date: April 2011
• Est. primary completion date: April 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

• 20<age<80

• apparently healthy subjects

Exclusion Criteria:

• a history of cardiovascular disease

• diabetes

• stage 2 hypertension

• malignancy

• severe renal or hepatic disease

Study Design

Observational Model: Cohort, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Sarcopenia

Locations

Country	Name	City	State
Korea, Republic of	Korea University Guro Hospital	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Korea University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Serum concentration of irisin in the subjects with sarcopenia		12 week	No
Secondary	The relationship of serum irisin levels with lipid profiles		12 week	No
Secondary	The relationship of serum irisin levels with skeletal muscle mass index		12 wks	No