MaSS - Maastricht Sarcopenia Study

Sarcopenia Clinical Trial

— MaSS  

Official title:

Cross-sectional Study on the Identification and Characterization of Community-dwelling Older People With Sarcopenia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01820988
• Other study ID #: METC 13-3-006
• Status: Completed
• Phase: N/A
• First received: March 12, 2013
• Last updated: January 18, 2016
• Start date: May 2013
• Est. completion date: December 2015

Study information

• Verified date: April 2015
• Source: Maastricht University Medical Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
• Study type: Observational

Clinical Trial Summary

The objective of this cross-sectional study is to obtain insight in the characteristics (nutritional status and level of physical activity) of sarcopenic compared to non-sarcopenic community-dwelling older people. There is one measurement moment and measurements will take place at the participant's home.

Description:

• Characterization of sarcopenic older people (demographics, nutritional status, level of physical activity)

• Prevalence rates of sarcopenia in community-dwelling older people in the Netherlands

• Insight in differences and/or overlap between sarcopenia versus frailty

• Insight in the impact of sarcopenia on economic outcomes

Recruitment information / eligibility

• Status: Completed
• Enrollment: 247
• Est. completion date: December 2015
• Est. primary completion date: March 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 65 Years to 99 Years

Eligibility

Inclusion Criteria:

• = 65 years old

• Have given informed consent

• Understand Dutch language

• Able to perform a walk test

Exclusion Criteria:

• Older people living in a nursing home

• Older people with active rheumatoid arthritis, post stroke status with evident lingering symptoms (paralysis, loss of motor functions), diseases of the nervous system like Parkinson and MS, active angina pectoris, dementia

• Older people in a wheelchair, with ICD or pacemaker

Study Design

Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Sarcopenia

Locations

Country	Name	City	State
Netherlands	Maastricht University	Maastricht

Sponsors (2)

Lead Sponsor	Collaborator
Maastricht University Medical Center	Nutricia Research Fundation

Country where clinical trial is conducted

Netherlands, 

References & Publications (2)

Mijnarends DM, Meijers JM, Halfens RJ, ter Borg S, Luiking YC, Verlaan S, Schoberer D, Cruz Jentoft AJ, van Loon LJ, Schols JM. Validity and reliability of tools to measure muscle mass, strength, and physical performance in community-dwelling older people — View Citation

Mijnarends DM, Schols JM, Meijers JM, Tan FE, Verlaan S, Luiking YC, Morley JE, Halfens RJ. Instruments to assess sarcopenia and physical frailty in older people living in a community (care) setting: similarities and discrepancies. J Am Med Dir Assoc. 201 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mean difference in nutritional status and level of physical activity of sarcopenic participants vs. non-sarcopenic participants, as a measure of a Food Frequency Questionnaire and Mini-Nutritional Assessment Tool and Minnesota questionnaire		1 home visit	No
Secondary	Prevalence of sarcopenia in community-dwelling older people		1 home visit	No
Secondary	Number of sarcopenic participants with frailty as a measure of the FRAIL scale and Fried criteria		1 home visit	No
Secondary	Health care costs by sarcopenic vs. non-sarcopenic participants, measured by health care use		1 home visit	No