Sarcopenia Clinical Trial
Official title:
Impact of Acute Low Intensity Exercise and Protein Intake on Skeletal Muscle Protein Synthesis in Elderly: a Randomized Controlled Trial
Maintenance of skeletal muscle mass is crucial during lifespan to retain health and
functional autonomy. Sarcopenia, being the loss of muscle mass during aging, is a well-known
phenomenon in the elderly and a major challenge viewed from an individual, and a
socioeconomic point of view. Nevertheless, several studies have proved muscle tissue to be
markedly affected by physical activity and nutritional interventions even at old age.
Recently, a study in young individuals showed that an acute bout of easily tolerated low
intensity exercise can prolong the muscle building effects of a milk protein intake compared
to a non-exercised situation. Therefore, the major aim of the present project is to
evaluate, whether a low intensity exercise regime in conjunction with milk protein
supplementation can induce positive adaptations on parameters related to muscle size and
function in elderly.
The study focuses on the acute muscle protein synthesis response to low intensity exercise
and protein supplementation measured with stable isotope tracer techniques. It is
hypothesized that light muscle activity can augment and prolong the effects of protein
feeding.
If a light resistance exercise protocol as investigated in the present project can prove
beneficial, elderly, frail elderly, and individuals undergoing rehabilitation can challenge
sarcopenia in a new and tolerable way.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
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