Fit in the Aged by Professional Training

Sarcopenia Clinical Trial

— FiAT  

Official title:

The Effect of Different Training Modalities and Vitamin D Supplementation on Functionality in Prefrail Elderly Persons

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00783159
• Other study ID #: 32.5.8051.0113.0
• Status: Completed
• Phase: N/A
• Start date: June 2008
• Est. completion date: May 2010

Study information

• Verified date: December 2020
• Source: University of Erlangen-Nürnberg Medical School
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This intervention study tests training methods to stabilize or improve functionality in the high risk group of prefrail elderly persons.

Description:

This study aims at the improvement of muscular function by physical exercise in prefrail elderly persons. Prefrail participants are recruited according to the frailty score of Fried. Taking into account, that vitamin D supplementation reduces falls and improves muscle strength in older people, all participants are supplemented by vitamin D. Two different training methods are tested.

After a run-in period of supplementation of vitamin D for two months, participants will be randomized into three different equally sized groups (n=25): Group A will receive power training. Group B will have progressive strength training. Group C will serve as a control group. They will receive a consultation about leading a healthy life with special attention being paid to nutrition and physical activity. The intervention period lasts for 12 weeks. The 60 minutes training sessions will be held two times a week by members of the Institute of Sport Science and Sports of the University of Erlangen-Nuremberg. Follow-up visits are scheduled three and six months after intervention period.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 69
• Est. completion date: May 2010
• Est. primary completion date: December 2009
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Prefrailty according to the frailty score of Fried

Exclusion Criteria:

• Sarcoidosis

• Nephrolithiasis

• Plasmacytoma

• COPD

• Inflammatory bowel disease

• Rheumatoid arthritis

• History of cancer

• Instable heart disease

• Depression (GDS>=6)

• Dementia (MMSE<=24)

• BMI>35kg/m²

• Current attendance of muscle training

• Medication: immunosuppressive drugs

Related Conditions & MeSH terms

• Frailty
• Sarcopenia

Intervention

Procedure:
• Power Training
Power training, Vitamin D substitution
• Strength Training
Strength training, Vitamin D substitution

Other:
• Control
Vitamin D substitution, Lifestyle consultation

Locations

Country	Name	City	State
Germany	Institute of Biomedicine of Aging	Nuremberg

Sponsors (6)

Lead Sponsor	Collaborator
University of Erlangen-Nürnberg Medical School	Institute of Biomedicine of Aging, Institute of Sport Science and Sport, Klinikum Nürnberg, Robert Bosch Medical Center, University of Erlangen-Nürnberg

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Short physical performance battery		3 months after intervention
Secondary	Muscle strength and muscle power		3 months after intervention