The Sarcoma Biology and Outcome Project — SarcBOP  

Sarcoma Clinical Trial

Official title: A Prospective Registry Study on Biological Disease Profile, Intervention Type and Clinical Outcome in Adolescent and Adult Patients With Soft-tissue and Bone Sarcoma

Status Recruiting

Clinical Trial Summary

SarcBOP - An interdisciplinary and translational registry

SarcBOP aims to establish a database that integrates every aspect possibly relevant to sarcoma treatment and research. SarcBOP thus will not be limited to specific questions or patient groups, but instead will build a comprehensive database including clinical, pathologic, and radiologic information, multi-layered molecular data, and patient-reported outcomes, combined with a dedicated biobank for tissue samples and liquid biopsies. As the study integrates seamlessly with the clinical activities of the Heidelberg Sarcoma Center, the Molecular Diagnostics Program of NCT Heidelberg, including the NCT/DKTK MASTER Program, and with the NCT Trial Center, including the PMO Clinical Trials Program, SarcBOP will generate a comprehensive and continuously growing resource for clinicians, researchers, and, finally, patients.

Clinical Trial Description

The following data are collected and stored:

• Demographics

• Comorbidities

• Clinical characteristics at diagnosis, relapse and progression

• Radiologic images

• Histological images

• Treatments including DRG and OPS data, including detailed information on surgical, radiation, and medical therapy as well as treatment relevant follow-up data

• Longitudinal disease assessments

• Clinical outcome

• Genomic, transcriptomic, epigenomic and proteomic data

• Patient reported outcomes

Furthermore, biological samples are collected and processed by the Sample Processing Laboratory of the Heidelberg Center for Personalized Oncology and the NCT Biobank. ;

Related Conditions & MeSH terms

• Malignant Mesenchymoma
• Sarcoma
• Sarcoma of Bone and Connective Tissue

• NCT number: NCT04758325
• Study type: Observational [Patient Registry]
• Source: University Hospital Heidelberg
• Contact: Richard F. Schlenk, Prof.Dr.med
• Phone: +49 6221 56 6228
• Email: richard.schlenk@med.uni-heidelberg.de
• Status: Recruiting
• Start date: July 23, 2019
• Completion date: December 31, 2032