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Sarcoidosis, Pulmonary clinical trials

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NCT ID: NCT05368883 Active, not recruiting - Clinical trials for Pulmonary Sarcoidosis

Comparison of the Effects of One-Legged and Two-Legged Exercise Training on Exercise Capacity and Fatigue in Patients With Sarcoidosis

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Pulmonary rehabilitation is a key element in the management of people with chronic respiratory disease. A properly followed supervised physical training program in sarcoidosis is safe and has no absolute contraindications. Fatigue can also be associated with sarcoidosis for different reasons. Individualized rehabilitation training can improve the symptoms of patients with sarcoidosis. There is no study in the literature investigating the effectiveness of one-legged exercises that reduce peripheral muscle use, in patients with sarcoidosis. In our study, these two exercise methods will be compared by applying one-legged exercise training and two-legged exercise training. The effect of one-legged exercise training on exercise capacity and fatigue in sarcoidosis patients will be examined. The primary aim of our study is to compare the effects of one-legged exercise training, which is a current exercise approach, and two-legged exercise training on exercise capacity and fatigue in patients with sarcoidosis. The secondary aim is to examine the effect of this exercise training on peripheral muscle strength and quality of life parameters.

NCT ID: NCT05314517 Active, not recruiting - Clinical trials for Sarcoidosis, Pulmonary

A Study to Assess the Efficacy and Safety of Namilumab in Participants With Chronic Pulmonary Sarcoidosis

RESOLVE-Lung
Start date: August 31, 2022
Phase: Phase 2
Study type: Interventional

This is a randomized, double-blind, placebo-controlled study with an open-label extension (OLE).

NCT ID: NCT04314193 Active, not recruiting - Clinical trials for Sarcoidosis, Pulmonary

Effectiveness of Methotrexate Versus Prednisolone as First-line Therapy for Pulmonary Sarcoidosis

PREDMETH
Start date: June 1, 2020
Phase: Phase 4
Study type: Interventional

This is a prospective, randomized, non-blinded, multi-center, non-inferiority trial designed to compare effectiveness and side-effects of methotrexate versus prednisolone as first-line therapy for pulmonary sarcoidosis..

NCT ID: NCT03755245 Active, not recruiting - Clinical trials for Rheumatoid Arthritis

Biodistribution, Dosimetry and Performance of [68Ga]Ga-DOTA-Siglec-9 in Healthy and Patients With Rheumatoid Arthritis, Vasculitis or Pulmonary Sarcoidosis

SIGLEC
Start date: November 23, 2018
Phase: N/A
Study type: Interventional

This study evaluates safety, tolerability, biodistribution and performance of the [68Ga]Ga-DOTA-Siglec-9 following a single intravenous administration in patients with active rheumatoid arthritis, vasculitis or pulmonary sarcoidosis as well as radiation dosimetry, plasma pharmacokinetics, biodistribution, safety and tolerability of the tracer in healthy volunteers.