Saliva Clinical Trial
Official title:
Evaluation of IL-2, IL-5 and IL-17 Expression Levels in Saliva of Patients Treated With Stainless Steel Crowns
The aim of this study is to investigate whether nickel hypersensitivity following stainless steel crown treatment in children aged 7-13 leads to an increase in IL-2, IL-5, and IL-17 levels by analyzing saliva samples. By doing so, the study seeks to prevent potential hypersensitivity reactions after stainless steel crown treatment. The main question it aims to answer is: Which interleukin level increases in the controls 1 week after stainless steel crowns are applied? Researchers will investigate whether there is a significant increase in interleukin levels in children's saliva before and after the procedure. Participants will: They will provide saliva samples before stainless steel crowns are applied They will visit the clinic after 1 week for check-ups and tests.
Expression levels of IL-2, IL-5 and IL-17 in the saliva of individuals aged 7-13 years who underwent stainless steel crown will be recorded before and after the procedure. Before the saliva sample collection procedure, the patient will be asked to rinse their mouth with sterile water and then spit into sterile plastic cups. After collecting approximately 3 ml of saliva, the saliva will be transferred to appropriate eppendorfs and stored at -40 degrees Celsius. For the second post-procedure, the same algorithms will be applied for saliva collection seven days after the crown procedure. Also ph value and ion levels of saliva will be measured ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02554604 -
Identifying HDL Composition and Function in Preeclamptic and Normal Pregnancies
|
||
Completed |
NCT04670341 -
The Effect of Chewing the Tapioca Pearls in Bubble Tea Drinks
|
N/A | |
Completed |
NCT06437262 -
Antibacterial Effect and Substantivity of a New Chlorhexidine and Cymenol Gel on Oral Biofilm and Saliva
|
Phase 1 | |
Recruiting |
NCT06047132 -
PREDICTIVE ABILITY OF A PANEL OF BIOMARKERS IN SALIVA IN HEALTHY AND PERIODONTALLY AFFECTED SUBJECTS
|
||
Completed |
NCT05635929 -
Oral Mucositis and Quality of Life With a Mucosa Topical Composition in Head & Neck Cancer Patients.
|
N/A | |
Not yet recruiting |
NCT06276335 -
Influence of Timing of Implant Placement on Early Healing Molecular Events
|
N/A | |
Recruiting |
NCT06037603 -
Dual-Task Exercise for Mild Traumatic Brain Injury (mTBI)
|
N/A | |
Recruiting |
NCT05791149 -
Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity
|
N/A | |
Completed |
NCT05325983 -
Using Saliva Stimulation to Immediately Improve Heart Failure Inpatient's Thirst Sensation
|
N/A | |
Completed |
NCT03612414 -
Efficacy of a Dietary Supplement (Aqualief®) in Xerostomic Patients
|
N/A | |
Recruiting |
NCT06354205 -
Comparison of Salivary Procalcitonin (PCT) Levels and Serum PCT Levels
|
N/A | |
Completed |
NCT04721457 -
The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load
|
Phase 4 | |
Completed |
NCT02149758 -
EFFECT OF SELECTIVE COX-2 INHIBITOR (ETORICOXIB) ALONG WITH SCALING AND ROOT PLANING (SRP) ON CLINICAL PARAMETERS AND SALIVARY LEVEL OF SUPEROXIDE DISMUTASE IN CHRONIC GENERALIZED PERIODONTITIS A DOUBLE-BLIND, PLACEBO-CONTROLLED, DOUBLE-MASKED RANDOMIZED CONTROLLED TRIAL (RCT).
|
Phase 4 | |
Completed |
NCT05437874 -
Carbonated Beverage Consumption in pH and Bacterial Proliferation
|
Phase 1 | |
Completed |
NCT05793099 -
Effect of 5% Aqueous Propolis in Salivary and Dental Plaque pH in Children
|
N/A | |
Recruiting |
NCT05890469 -
Effect of Implant Surface Material and Topography on Bone Regeneration.
|
N/A | |
Completed |
NCT04352959 -
COVID-19: Nasal and Salivary Detection of the SARS-CoV-2 Virus After Antiviral Mouthrinses
|
N/A |