Gingivitis Clinical Trial
Official title:
Effects of Two Sugar Substituted Chewing Gums Plus Tooth Brushing on Different Caries and Gingivitis Related Variables: a Double Blind, Randomized Controlled Clinical Trial
The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.
The purpose of this paper is to compare the effect of daily consumption of two sugar-free
chewing gum, one with Recaldent and one with Xylitol, added to traditional hygiene
(brushing, fluoridated toothpaste and dental floss), in clinical features such as the
accumulation of plaque and gingival inflammation, microbiological characteristics of saliva
as the counts of cariogenic microorganisms and facultative anaerobes, and some
physicochemical properties of saliva such as pH and concentrations of calcium and inorganic
phosphate.
To this there was a general call among dental students at the University of Antioquia and
those who expressed their intention to participate voluntarily with informed consent, were
examined clinically and randomly assigned to one of the study groups (Recaldent or Xylitol)
or the control group.
After a month of baseline examination and the daily use of the same instruments of oral
hygiene and chewing of 6 pellets of each chewing gum (in the case of study groups), all
variables are re-examined.
;
Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
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