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Clinical Trial Summary

To study the effect and saftey of intratracheal instillation of mesenchymal stem cells for treatment BPD


Clinical Trial Description

This is a Phase 1 clinical trial that constitues two points cohorts with 100 participants per cohort who will receive instillation dose of mesenchymal stem cells-25 million cells/kg,with ventilation after 14 days.And the placebol will be 0.9% sodium choride. The investigator will proceed the groups during the same period.

1. Deographic Data and Baseline charateristics of the studied groups were collected:

Gestational age (weeks) Birth weight (g) gender Cesarean section delivery Antenatal steroids Prolonged rupture of membrane Multiple pregnancies APGAR score at 5 minutes

2. mesenchymal stem cels dose is 25 million cells/kg

3. Assessment the incidence of BPD after instillation of Mesenchymal stem cells

4. the adverse after instillation of Mesenchymal stem cells ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03683953
Study type Interventional
Source Guangdong Women and Children Hospital
Contact Zhuxiao Ren, MD
Phone +8613538984634
Email renzhx1990@163.com
Status Not yet recruiting
Phase Phase 1
Start date September 29, 2018
Completion date July 1, 2020

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