Safety Issues Clinical Trial
Official title:
The Treatment of Bronchopulmonary Dysplasia by Intratracheal Instillation of Mesenchymal Stem Cells
To study the effect and saftey of intratracheal instillation of mesenchymal stem cells for treatment BPD
This is a Phase 1 clinical trial that constitues two points cohorts with 100 participants per
cohort who will receive instillation dose of mesenchymal stem cells-25 million cells/kg,with
ventilation after 14 days.And the placebol will be 0.9% sodium choride. The investigator will
proceed the groups during the same period.
1. Deographic Data and Baseline charateristics of the studied groups were collected:
Gestational age (weeks) Birth weight (g) gender Cesarean section delivery Antenatal
steroids Prolonged rupture of membrane Multiple pregnancies APGAR score at 5 minutes
2. mesenchymal stem cels dose is 25 million cells/kg
3. Assessment the incidence of BPD after instillation of Mesenchymal stem cells
4. the adverse after instillation of Mesenchymal stem cells
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