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RSV Infection clinical trials

View clinical trials related to RSV Infection.

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NCT ID: NCT04782336 Suspended - Covid19 Clinical Trials

Sample Collection Study to Aid Evaluation of an Influenza A/B, Respiratory Syncytial Virus & COVID-19 Virus POC Test

INFORM
Start date: December 12, 2020
Phase: N/A
Study type: Interventional

Collection of Nasal Swabs, Throat Swabs and Saliva Samples from patients presenting at their designated care or testing facility displaying symptoms of either Influenza, Respiratory Syncytial Virus (RSV), SARS-CoV-2 or those who have been in recent contact with SARS-CoV-2 positive patients. Collected samples will aid the development, calibration and performance evaluation of the LumiraDx POC Test.

NCT ID: NCT04752644 Completed - RSV Infection Clinical Trials

Phase 2a Study of MVA-BN-RSV Vaccination and RSV Challenge in Healthy Adults

Start date: February 22, 2021
Phase: Phase 2
Study type: Interventional

A Phase 2a, Randomised, Double-Blinded, Placebo-Controlled Study to Assess the Safety, Immunogenicity and Efficacy of the Recombinant MVA-BN®-RSV Vaccine against Respiratory Syncytial Virus Infection in the Virus Challenge Model in Healthy Adult Participants

NCT ID: NCT04743609 Recruiting - Pneumonia Clinical Trials

RSV Burden in Outpatient Settings

Oursyn
Start date: February 8, 2021
Phase:
Study type: Observational

Strengthening outpatient low respiratory tract infection surveillance to document the burden of Respiratory Syncytial Virus (RSV)

NCT ID: NCT04690335 Completed - RSV Infection Clinical Trials

Human Challenge Study to Evaluate the Efficacy of MV-012-968 Vaccine

Start date: December 29, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this research study is to evaluate whether the investigational, live attenuated, intranasally delivered vaccine MV-012-968 ('study vaccine') may have prophylactic efficacy against symptomatic RSV infection when administered to adults 18-45 years of age in the Human Viral Challenge model.

NCT ID: NCT04531735 Active, not recruiting - Covid19 Clinical Trials

Respiratory Syncytial Virus Infection May be More Dangerous in Neonate

Start date: March 1, 2020
Phase:
Study type: Observational

Investigators aimed to compare clinical and radiographic markers between SARS-CoV-2 positive and RSV positive infants

NCT ID: NCT04520659 Active, not recruiting - RSV Infection Clinical Trials

Evaluating the Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine, LID/ΔM2-2/1030s, in RSV-Seronegative Infants and Children 6 to 24 Months of Age

Start date: February 23, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the infectivity, safety, and immunogenicity of a single dose of a recombinant, live-attenuated respiratory syncytial virus (RSV) vaccine, LID/ΔM2-2/1030s, in RSV-seronegative infants and children 6 to 24 months of age.

NCT ID: NCT04498741 Completed - RSV Infection Clinical Trials

Drug-Drug Interaction Study Between EDP-938, Tacrolimus, Dabigatran, Rosuvastatin and Midazolam in Healthy Subjects

Start date: July 8, 2020
Phase: Phase 1
Study type: Interventional

A Non-Randomized, Open-Label, Three-Part, Drug-Drug Interaction Study to Evaluate the Effects of tacrolimus, dabigatran, rosuvastatin and midazolam on the Pharmacokinetics and Safety of EDP-938 in Healthy Subjects

NCT ID: NCT04484935 Completed - RSV Infection Clinical Trials

Evaluate the Safety and Tolerability, for Nirsevimab in Immunocompromised Children

MUSIC
Start date: August 19, 2020
Phase: Phase 2
Study type: Interventional

Study D5290C00008 is a Phase 2, open-label, uncontrolled, single-dose study to evaluate the safety and tolerability, pharmacokinetic(s) (PK), occurrence of antidrug antibody (ADA), and efficacy of nirsevimab in immunocompromised children who are ≤ 24 months of age at the time of dose administration. Approximately 100 subjects will be enrolled. Subjects will be followed for approximately 1 year after dose administration.

NCT ID: NCT04267822 Withdrawn - Clinical trials for Stem Cell Transplant Complications

Study of RV521 in the Treatment of Adult Subjects Who Have Undergone HCT With an URTI With RSV

REVIRAL2
Start date: June 15, 2020
Phase: Phase 2
Study type: Interventional

RV521 is to being developed to treat RSV infection and disease in susceptible individuals at high risk for complications. This is an international, multicenter, placebo-controlled study. Eligible subjects are adults with a documented symptomatic RSV infection who have undergone HCT transplantation and are moderately to severely immunocompromised. Qualified subjects will be randomized in a 1:1 ratio to receive RV521 or placebo, twice daily for 10 days.

NCT ID: NCT04144816 Not yet recruiting - Clinical trials for Respiratory Syncytial Virus Infections

Predictors of Respiratory Syncytial Virus (RSV) Hospitalizations in Infants

PRSVH
Start date: October 2019
Phase:
Study type: Observational

The VRS (Respiratory Syncytial Virus) study group in Lyon is a working that aims to understand, predict and prevent the burden of disease caused by human respiratory syncytial virus (RSV) infection in infants. Incidence of RSV-associated hospitalization in the first year of life was estimated at 14.5 (95% CI 13.4-15.6) per 1000 births in a cohort study in Lyon, France. Related direct medical annual costs were estimated for this cohort at 364,269€, mostly attributed to children born during the RSV season (231,959€) and children born premature (108,673€). This study will combine existing hospital specimens and databases to determine the respective role of socio demographic factors, clinical risk factors, level of cord specific antibody at birth, and virus characteristic in the Respiratory Syncytial Virus (RSV) Hospitalization outcome in Infants. Regarding the introduction of a new RSV vaccine and RSV-specific neutralizing antibodies, these data are of prime importance to guide future vaccine policies.