Frequency Analysis of the Ultrasound Images in Rotator Cuff Tendon

Status Not yet recruiting

Clinical Trial Summary

Previous studies used spatial frequency analysis of tendon ultrasound images and considered that the parameters can reflect the micro-structure of the tendon. In this study, we try to recruit and analysis the rotator cuff tendon in healthy adults with different ages and different equipment to explore the the normal range and differences of spatial frequency parameters. The hypotheses of this study are (1) the young and the elderly would have significantly different spatial frequency value; and (2) there would be significant different results between different equipment.

Clinical Trial Description

Tendons are hierarchical fibrous tissues. The speckle signals of ultrasonic images have parallel stripes arranged along the long axis of the tendon, reflecting the arrangement of collagen fiber bundles in the tendon. The micro-structure of tendons can be quantified by analyzing the speckle pattern of ultrasonic images. A research team used fast Fourier transform to convert ultrasound images of tendons into two-dimensional spatial frequency spectra, and used linear discriminate analysis to calculate multiple spatial frequency parameters. The results indicated that there were 5 parameters with the highest accuracy in discriminating Achilles tendinopathy. There is a significant difference in the spectrum frequency parameters of whether the tendon was loaded and whether there was a tendinopathy tendon. Past studies using spatial frequency analysis in patients with shoulder pain, and they found that there was no significant difference between the asymptomatic control group and shoulder pain patients. The risk factors of rotator cuff tendon injury is related advanced age, dominant hand, and repeated overhead activities. Therefore, in this study, we will recruit participants of different ages and investigate the results of spatial frequency analysis of bilateral shoulders ultrasound images. The aim of this study is to know whether these factors may affect the micro-structure of the rotator cuff tendons and establish the reference norm of spatial frequency analysis parameters in those without obvious tendon degeneration or injury. In addition, we aim to compare the differences between spectrum analysis parameters with several instruments by using different ultrasonic equipment. This study could provide a reference for the clinical application of spatial frequency analysis in tendon ultrasound images. ;

Study Design

Related Conditions & MeSH terms

Rotator Cuff Injuries

Clinical Trial Details

NCT number	NCT04859413
Study type	Observational
Source	National Taiwan University Hospital
Contact	Chao Yuan-Hung, PhD
Phone	0933121572
Email	yuanhungchao@ntu.edu.tw
Status	Not yet recruiting
Phase
Start date	April 2021
Completion date	September 2021

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06039345` - Shoulder RFA Pilot Study
Completed	`NCT06070493` - The Effects of Myofascial Release Technique	N/A
Completed	`NCT04541953` - TeleRehabilitation Following Arthroscopic Rotator Cuff Repair	N/A
Completed	`NCT04944446` - Myofascial Release in Shoulder Pathologies	N/A
Recruiting	`NCT06112444` - Validity And Reliability Study Of The Turkish Version Of Short Western Ontario Rotator Cuff Index
Completed	`NCT04594408` - Tranexamic Acid to Improve Arthroscopic Visualization in Shoulder Surgery	Phase 4
Active, not recruiting	`NCT04686396` - Demineralized Bone Matrix Rotator Cuff Study	N/A
Recruiting	`NCT05988541` - Rotator Cuff Integrity and Clinical Outcomes 5 Years After Repair.	N/A
Completed	`NCT04470167` - Phase 1/2 Clinical Study of TPX-115 in Patients With Partial-Thickness Rotator Cuff Tear	Phase 1/Phase 2
Recruiting	`NCT05297305` - Onlay Versus Inlay Humeral Component in Reverse Total Shoulder Arthroplasty	N/A
Completed	`NCT02528084` - The Effects of Yoga on Patients With Rotator Cuff Injuries	N/A
Recruiting	`NCT05011331` - The Effect of a Custom Pillow on Sleep Quality in Patients With Nonoperative Rotator Cuff Syndrome	N/A
Recruiting	`NCT04209504` - Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
Completed	`NCT03967574` - Subacromial Corticosteroid Injections and tDCS in Rotator Cuff Tendinopathy	N/A
Completed	`NCT04952623` - Online Education to Improve the Management of Rotator Cuff Related Shoulder Pain	N/A
Recruiting	`NCT05344898` - Subscap Reverse Shoulder Arthroplasty	N/A
Recruiting	`NCT04175184` - Inclusion of Mobilisation With Movement to an Exercise Programme in Rotator Cuff Related Pain	N/A
Active, not recruiting	`NCT05215600` - Anaverse™ Glenoid System and Its Instrumentation
Recruiting	`NCT05822414` - ESP vs STB for Pain and Diagraphragm Function for Shoulder Surgery	N/A
Completed	`NCT03982108` - Comparison of Two Arthroscopic Rotator Cuff Repair Techniques: Knot-tying Versus Knotless Suture-bridge Technique	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.