Rosacea Clinical Trial
Official title:
Therapeutic Effects of Topical Herbal Medicine on Rosacea
The aim of this study is to investigate the effects of topical herbal medicine in the patients with rosacea.
Status | Recruiting |
Enrollment | 24 |
Est. completion date | August 4, 2023 |
Est. primary completion date | August 4, 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years and older |
Eligibility | Inclusion Criteria: - Willing to sign inform consent - Aged above 20 years old with rosacea - No treatment for rosacea within 2 weeks Exclusion Criteria: - With malignant lesion in the rosacea lesion - Rosacea lesion with high risk of infection - Allergy to Chinese herbal medicine patch or ointment - Pregnancy |
Country | Name | City | State |
---|---|---|---|
Taiwan | Keelung Chang Gung Memorial Hospital | Keelung |
Lead Sponsor | Collaborator |
---|---|
Chang Gung Memorial Hospital |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | reduction of flushing, erythema, telangiectasia, papules, and pustules | quantified by Investigator Global Assessment, IGA. IGA is used in the study for assessing the severity of rosacea ranging from 0 (clean) to 4 (most severe). | 6 weeks | |
Primary | absence of adverse skin reaction to topical medicine | scored with Dyshidrotic Eczema Area and Severity Index (DASI index). The total score of the DASI results from the sum of severity grade score points of each of the four items (V = vesicles, E = erythema, S = desquamation, I = itch) multiplied by the affected area (A) score points: DASI = (pV + pE + pS + pI) × pA.
The maximum possible score is 60. By the DASI, the dyshidrotic eczema is graded as: mild (0-15), moderate (16-30) and severe (31-60). |
6 weeks | |
Secondary | improvement of life quality | Dermatology Quality of Life Index, DQoL is the questionnaire which designed to measure the health-related quality of life of adult patients suffering from a skin disease ranging from 0(no effect at all on patient's life) to 30(extremely large effect on patient's life). | 6 weeks |
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