Rosacea Clinical Trial
Official title:
Clinical Correlation Between Facial Demodicosis and Ocular Demodicosis
To understand the association between facial demodicosis and ocular demodicosis, we plan to enroll patients with facial demodicosis, ocular demodicosis, or both, in order to analyze their clinical presentations, the density of Demodex infestation over facial skin and eyelashes, and possible risk factors of the two diagnoses.
Although facial demodicosis and ocular demodicosis are described in a variety of clinical
presentations, the association between the two diagnoses is not clearly identified.
Clinically, we plan to enroll 120 patients with facial demodicosis, ocular demodicosis. We
will obtain their basic information, medical history, medication, and lifestyle. We will
evaluate their clinical features. We will also perform quantitative tests including direct
microscopic examination and cilia epilation test:
1. Direct microscopic examination: On glabella and bilateral cheeks, follicular contents in
the 1-cm × 1‐cm area will be squeezed out. The contents are transferred onto a glass
slide, covered with mineral oil and a cover slide, and examined under the microscope.
2. Epilation: Four (4) non-adjacent cilia will be pulled from each upper eyelid and
examined under the microscope. The total Demodex counts are recorded.
We will analyze the clinical presentations, the density of Demodex infestation, and possible
risk factors of the two diagnoses.
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