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Rosacea clinical trials

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NCT ID: NCT01494467 Completed - Clinical trials for Papulopustular Rosacea

Phase 3 Papulopustular Rosacea Study

Start date: December 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate that CD5024 1% cream is more effective than its vehicle when applied once daily, at bed time, during a 12 week period in subjects with Papulopustular Rosacea (PPR) and continues to be safe up to 12 months.

NCT ID: NCT01493947 Completed - Clinical trials for Papulopustular Rosacea

CD5024 1% [Ivermectin 1%] Cream Versus Metronidazole 0.75% Cream in Papulopustular Rosacea (PPR) Study

ATTRACT
Start date: April 2012
Phase: Phase 3
Study type: Interventional

Study objectives: - To compare efficacy and safety of Ivermectin 1% cream versus metronidazole 0.75% cream in subjects with papulopustular rosacea after 16-week topical treatment. - And to compare, for subjects initially successfully treated by 16 weeks treatment, Ivermectin 1 % cream versus metronidazole 0.75% cream during a 36-week extension period by assessing, the time of first relapse, the relapse rate, and the number of days free of treatment

NCT ID: NCT01493687 Completed - Clinical trials for Papulopustular Rosacea (PPR)

Phase 3 Papulopustular Rosacea Study

Start date: December 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate that CD5024 1% cream is more effective than its vehicle when applied once daily, at bed time, during a 12 week period in subjects with Papulopustular Rosacea (PPR) and continues to be safe up to 12 months.

NCT ID: NCT01451619 Completed - Rosacea Clinical Trials

A Study of Laropiprant (MK-0524) in Participants With Moderate to Severe Erythematotelangiectatic Rosacea (MK-0524-155)

Start date: November 2011
Phase: Phase 1
Study type: Interventional

This study will assess the effect of MK-0524 relative to placebo, on signs and symptoms of rosacea and to determine the safety and tolerability profile of MK-0524 in participants with rosacea.

NCT ID: NCT01449591 Completed - Clinical trials for Erythemato-telangiectatic Rosacea

Safety, Tolerability and Efficacy of BFH772 in Rosacea Patients

Start date: September 2011
Phase: Phase 2
Study type: Interventional

This study will evaluate the safety, tolerability and efficacy of BFH772 after 12 weeks of treatment as compared to an active control and vehicle in patients with erythemato-telangiectatic rosacea.

NCT ID: NCT01426269 Completed - Rosacea Clinical Trials

Evaluation of Relapse, Efficacy and Safety of Long-term Treatment With Oracea® vs Placebo

Start date: September 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess relapse, efficacy and safety in subjects with rosacea during long-term treatment with either Oracea® or placebo, after an initial 12-week regimen of Oracea® and MetroGel® 1%.

NCT ID: NCT01398280 Completed - Rosacea Clinical Trials

Effects of Aminocaproic Acid (ACA) on Rosacea-specific Inflammation

ACA
Start date: July 2011
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to determine the effect of topical aminocaproic acid on the immune system by assessing the levels of antimicrobial peptides in the skin of patients with rosacea. It is hypothesized that aminocaproic acid applied topically will alter the body's immune system in patients with rosacea by inhibiting activation of antimicrobial peptides.

NCT ID: NCT01355471 Completed - Rosacea Clinical Trials

Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Start date: May 2011
Phase: Phase 3
Study type: Interventional

This is a Phase 3 efficacy and safety study of CD07805/47 topical gel in subjects with facial erythema associated with rosacea. The study hypothesis is that CD07805/47 gel, applied topically once daily is more efficacious than vehicle and provides an acceptable safety profile in the treatment of facial erythema associated with rosacea.

NCT ID: NCT01355458 Completed - Rosacea Clinical Trials

Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Start date: May 2011
Phase: Phase 3
Study type: Interventional

Phase 3 efficacy and safety study of CD07805/47 topical gel in subjects with facial erythema associated with rosacea. The study hypothesis is that CD07805/47 gel, applied topically once daily is more efficacious than vehicle and provides an acceptable safety profile in the treatment of facial erythema associated with rosacea.

NCT ID: NCT01318733 Completed - Rosacea Clinical Trials

Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Start date: March 2011
Phase: Phase 3
Study type: Interventional

A long-term, open-label, non-comparative safety and efficacy study of CD07805/47 gel 0.5% once daily in subjects with moderate to severe facial erythema associated with rosacea.