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Clinical Trial Summary

The hypothesis is whether perineural dexamethasone and dexmedetomidine prolonged the duration of analgesia as compared with either perineural dexamethasone or perineural dexmedetomidine after TPVB.


Clinical Trial Description

Design: A prospective, randomized, controlled study Setting: Single-center university hospital. Participants: The study included 90 patients undergoing lobectomy under general anesthesia. Interventions: The patients were allocated randomly into the following 3 groups: 20 ml mixture of 37.5 mg ropivacaine with 5 mg dexamethasone (RS group) or 1 µg/kg dexmedetomidine (RM group), or with 1 µg/kg dexmedetomidine and 5 mg dexamethasone (RSM group). Ultrasound-guided TPVB was performed at 4 points-T4-5, T5-6, T6-7, and T7-8 of the surgical side; 5 mL of solution were injected at each point. Postoperatively, the PCIA was used as part of multimodal analgesia, and all patients recieve . ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04763434
Study type Interventional
Source Gansu Provincial Hospital
Contact wen jun yan, doctor
Phone 17361552758
Email yanwj2008@hotmail.com
Status Not yet recruiting
Phase Phase 4
Start date March 20, 2021
Completion date August 30, 2021

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