Clinical Trial Details
— Status: Not yet recruiting
Administrative data
| NCT number |
NCT05509920 |
| Other study ID # |
Giomer based barrier coat |
| Secondary ID |
|
| Status |
Not yet recruiting |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
October 2022 |
| Est. completion date |
December 2023 |
Study information
| Verified date |
August 2022 |
| Source |
Cairo University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
Guidelines proved that arresting and remineralization of the root surface caries is better
than weakening the tooth structure and restoring it. Manufacturer claims that PRG Barrier
Coat effectively treats dental hypersensitivity by providing immediate and long-lasting
relief. Also has the effect of eliminating the activity and sur-vival of pathogenic bacteria
and hardening the dentin tissue of the affected areas.
Description:
A light-cured varnish with extended protection time of up to 6 months, PRG barrier coat
incorporates proprietary GIOMER tech-nology, "Surface Pre-Reacted Glass" for high fluoride
release and re-charge, continuous release of fluoride, strontium, boron, sodium, aluminum,
and zinc, acid neutralization and anti-plaque benefits with excellent self-adhesive
abilities. The new material could be an alter-native to SDF varnish in root caries arrest to
overcome its unfavor-able color and taste.
Products containing S-PRG fillers have been developed in a wide variety of areas such as
tooth surface coating materials, seal-ants, restoration resins and dentifrices. The use of
these materials is also expected to have the effect of improving the properties of enamel. In
this seminar, we will introduce a new caries prevention using S-PRG filler The eluted ions
from the S-PRG filler containing materials exhibit various functions, such as prohibition of
biofilm attachment, anti-demineralization, remineralization, modification of apatite crystal,
and acid-buffering effect. Each ion was confirmed its function. Par-ticularly, Strontium,
Borate and Fluoride ions were involved during calcium phosphate nucleation to form modified
nano-hydroxyapatite. The acid buffering effect was shown with the borate ion. As the results
of those effects of ions, the various materials with S-PRG technology were proven to
con-tribute to increase the acid resistance and the caries prevention.
