The Effect of Human Adipose Tissue-derived MSCs in Romberg's Disease

Romberg's Disease Clinical Trial

Official title:
Preliminary Investigation of the Effect of Human Adipose Tissue-derived Mesenchymal Stem Cell in Progressive Hemifacial Atrophy(Romberg's Disease)

Status Completed

Clinical Trial Summary

The purpose of this study is to investigate the efficacy and safety of autologous transplantation of adipose tissue derived mesenchymal stem cells (MSCs) in patient with progressive hemifacial atrophy.

Clinical Trial Description

Adipose derived mesenchymal stem cells (AdMSCs) represent an attractive and ethical cell source for stem cell therapy.

With the recent demonstration of MSC homing properties, intramuscular aplications of MSCs to cell-damaged diseases have increased.

In a human clinical trial, five patients who had suffered a progressive hemifacial atrophy( Romberg's disease) were intramuscular administered autologous hAdMSCs (1×10e7 cells/500ul) with autologous microlipoinjection one time. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01309061
Study type	Interventional
Source	R-Bio
Contact
Status	Completed
Phase	N/A
Start date	March 2008
Completion date	February 2010

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