QRS Microfragmentation in ECG as Predictor of Mortality and Morbidity - a Retrospective Analysis

Risk Stratification Clinical Trial

Official title:

QRS Microfragmentation in ECG as Predictor of Mortality and Morbidity - a Retrospective Analysis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06011590
• Other study ID #: 1244/2022
• Status: Completed
• Start date: January 1, 2000
• Est. completion date: July 31, 2022

Study information

• Verified date: August 2023
• Source: Medical University Innsbruck
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Over the past decades, several ECG-based parameters have been identified as independent predictors of worsened prognosis in affected patients. In addition to visual assessment of morphology, methods of computer-based machine ECG analysis have gained importance in recent years. These methods allow the detection of systemic abnormalities in ECGs that are not visible to the naked eye. An example of this is provided by the so-called "QRS microfragmentations". The aim of this evaluation is to retrospectively collect all established as well as new quantitative and qualitative ECG parameters (such as QRS microfragmentation) in a large patient collective. Subsequently, after characterization of the patients, an independent multivariate risk prediction model should be developed based on computer-based ECG analysis using maschnine learning algorithms.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 150000
• Est. completion date: July 31, 2022
• Est. primary completion date: July 31, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients who presented to the Department of Internal Medicine at the Medical University in Innsbruck between 01.01.2000 and 31.07.2022 and received an ECG recording as part of routine clinical practice.
• Age = 18 years
• Residence in Austria

Exclusion Criteria:

• Insuffizient ECG Recording quality

Related Conditions & MeSH terms

• Risk Stratification

Intervention

Other:
• No intervention.
No intervention.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Medical University Innsbruck

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	All cause mortality	Death of any cause	between 01.01.2000 and 31.07.2022
Secondary	Hospitalization	Unplanned Hospitalization	between 01.01.2000 and 31.07.2022
Secondary	Lenght of hospital stay	Lenght of hospital stay	between 01.01.2000 and 31.07.2022