Clinical Trials Logo
  1. Home
  2. Rib Fractures
  3. NCT05105399

Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib Fractures

Rib Fractures Clinical Trial

Official title:
Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib Fractures: a Perspective Randomized Controlled Study

Clinical Trial Summary

In patients admitted following a trauma, the incidence of multiple rib fractures is reported to be 9,7%, and this can be even higher in high energy trauma like motor vehicle accidents (1). Pain deriving from rib fractures cause the patient to breath shallow in order to limit discomfort and this bring about negative consequences: shallow breathing and inability to clear secretions may cause pulmonary atelectasis eventually evolving to pneumonia. Given the aforementioned concerns, it is easy to understand why, in a context like this, control of chest pain become crucial. The best way to achieve adequate pain control have not yet been established: the aim of this study is to investigate on this clinical dilemma. In this study, 72 people with at least two monolateral rib fractures are going to be randomized into three groups: 1) standard treatment alone (intravenous analgesia: acetaminophen + morphine PCA); 2) continuous serratus plane block + standard treatment; 3) single-shot serratus plane block + standard treatment. The variables that are going to be recorded are the following: pain through the NRS scale, FEV1 and FVC through spirometry and finally an arterious gas analysis. Recording are going to be repeated at 72h after admission. The primary endpoint is to evaluate if the continuous serratus plane block is able to improve the FEV1/FVC compared to single shot or standard treatment alone. Secondary endpoints will be: the effect of continuous block on 1) resting and incident pain; 2) opioid consumption; 3) blood gas analysis parameters; 4) pulmonary complications at 1 month; 5) length of stay

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05105399
Study type Interventional
Source Niguarda Hospital
Contact Antonio Giorgi, MD
Phone +393208588471
Email antonio.giorgi@ospdaleniguarda.it
Status Not yet recruiting
Phase N/A
Start date June 1, 2024
Completion date May 1, 2025
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04554186 - Serratus Anterior Plane Block Versus Thoracic Paravertebral Block. N/A
Completed NCT02432456 - Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients Phase 4
Not yet recruiting NCT04168710 - Ultrasound Guided Emergency Physician Performed Erector Spinae Nerve Block for Rib Fracture Analgesia Phase 1/Phase 2
Recruiting NCT04413799 - PVB vs Ketamine/Lidocaine in Rib Fracture Patients Early Phase 1
Completed NCT05770232 - Retrospectively Analyze the Risk Factors of VTE in 5774 Patients With Thoracic Trauma From 33 Hospitals in China, and Established a Risk Prediction Model
Completed NCT03305666 - Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures Phase 4
Completed NCT03768193 - Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery N/A
Recruiting NCT05865327 - UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture N/A
Completed NCT06448078 - Comparative Evaluation of External Chest Wall Fixator Treatment Effectiveness in Patients With Rib Fractures N/A
Recruiting NCT04100512 - Oscillating Positive Expiratory Pressure (OPEP) Therapy in Trauma Patients With Multiple Rib Fractures N/A
Completed NCT02608541 - Sheffield Multiple Rib Fractures Study:
Completed NCT04168996 - Individualized Discharge Planning in Patients With Rib Fracture N/A
Recruiting NCT05714631 - Lidocaine Patches in Elderly Patients With Traumatic Rib Fractures Phase 4
Recruiting NCT03619785 - US-guided SAPB for Rib Fractures in the ED Phase 4
Suspended NCT03711812 - Serratus Anterior Block and Catheter Use in Rib Fractures in the Emergency Department N/A
Completed NCT05321121 - Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial Phase 4
Completed NCT04863807 - A Retrospective Review of Rib Fracture Pain Management at a London Major Trauma Centre
Withdrawn NCT05069961 - Non-Inferiority Study of Erector Spinae Plane Block Compared to Thoracic Epidural in Pain Management of Rib Fractures N/A
Recruiting NCT03919916 - Serratus Plane Block With Parenteral Opioid Analgesia Versus Patient Controlled Analgesia in Rib Fractures N/A
Terminated NCT03805360 - The Erector Spinae Plane Block and Its Effect on Respiratory Status and Pain Management in Rib Fracture Patients Phase 1