Surgical & Conservative Treatment in Isolated Minor Rib Fractures

Status Not yet recruiting

Clinical Trial Summary

The purpose of this research is to compare the outcomes of surgical stabilization and conservative treatment in patients with isolated minor rib fractures.

Clinical Trial Description

Isolated minor rib fractures (IMRFs), which is defined by single or two isolated minor rib fractures caused by trauma or stress. Traditionally, rib fractures are managed mainly by surgical stabilization or conservative treatment. In 2018, a systemic review and meta-analysis for patients with multiple rib fractures had revealed a shorter duration of mechanical ventilation, shorter hospital length of stay, and fewer trauma-associated complications in the surgical group than in the non-surgical group. In contrast, IMRFs are seldom life threatening, and compared to extremity fractures, rib fractures do not require matching accurately. Thus, IMRFs are usually treated conservatively. However, the investigators have clinically observed that patients suffering severe pain due to progressive rib displacement may take longer to return to normal activity, have lower quality of life, and even an increased risk of complications. Moreover, limited studies discussed the efficacy of surgical interventions for IMRFs. Therefore, the investigators conduct a prospective observational cohort study to compare the outcomes of surgical stabilization and conservative treatment in patients with IMRFs. The investigators collect patients with IMRFs whose situation were both suitable for surgical and non-surgical interventions. After explanation, patients can decide to undergo conservative or surgical treatment by themselves. The investigators will follow up pain scores, chest X-ray, pulmonary function tests, and duration of return to normal activity. Those data will be statistically analyzed by two-tailed two-sample t-test. This prospective cohort study is supposed to provide more evidence for clinical decision making and optimal management of IMRFs. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04104932
Study type	Observational [Patient Registry]
Source	Taipei Medical University Shuang Ho Hospital
Contact	Tung-Yu Tiong, MD
Phone	+886970747235
Email	dr_tiong@yahoo.com
Status	Not yet recruiting
Phase
Start date	July 2019
Completion date	October 30, 2023

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04554186` - Serratus Anterior Plane Block Versus Thoracic Paravertebral Block.	N/A
Completed	`NCT02432456` - Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients	Phase 4
Not yet recruiting	`NCT04168710` - Ultrasound Guided Emergency Physician Performed Erector Spinae Nerve Block for Rib Fracture Analgesia	Phase 1/Phase 2
Recruiting	`NCT04413799` - PVB vs Ketamine/Lidocaine in Rib Fracture Patients	Early Phase 1
Completed	`NCT05770232` - Retrospectively Analyze the Risk Factors of VTE in 5774 Patients With Thoracic Trauma From 33 Hospitals in China, and Established a Risk Prediction Model
Completed	`NCT03305666` - Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures	Phase 4
Completed	`NCT03768193` - Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery	N/A
Recruiting	`NCT05865327` - UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture	N/A
Completed	`NCT06448078` - Comparative Evaluation of External Chest Wall Fixator Treatment Effectiveness in Patients With Rib Fractures	N/A
Recruiting	`NCT04100512` - Oscillating Positive Expiratory Pressure (OPEP) Therapy in Trauma Patients With Multiple Rib Fractures	N/A
Completed	`NCT02608541` - Sheffield Multiple Rib Fractures Study:
Completed	`NCT04168996` - Individualized Discharge Planning in Patients With Rib Fracture	N/A
Recruiting	`NCT05714631` - Lidocaine Patches in Elderly Patients With Traumatic Rib Fractures	Phase 4
Recruiting	`NCT03619785` - US-guided SAPB for Rib Fractures in the ED	Phase 4
Suspended	`NCT03711812` - Serratus Anterior Block and Catheter Use in Rib Fractures in the Emergency Department	N/A
Completed	`NCT05321121` - Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial	Phase 4
Completed	`NCT04863807` - A Retrospective Review of Rib Fracture Pain Management at a London Major Trauma Centre
Withdrawn	`NCT05069961` - Non-Inferiority Study of Erector Spinae Plane Block Compared to Thoracic Epidural in Pain Management of Rib Fractures	N/A
Recruiting	`NCT03919916` - Serratus Plane Block With Parenteral Opioid Analgesia Versus Patient Controlled Analgesia in Rib Fractures	N/A
Terminated	`NCT03805360` - The Erector Spinae Plane Block and Its Effect on Respiratory Status and Pain Management in Rib Fracture Patients	Phase 1

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Surgical and Conservative Treatment in Isolated Minor Rib Fractures

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms