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Rhinosinusitis clinical trials

View clinical trials related to Rhinosinusitis.

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NCT ID: NCT00554190 Completed - Rhinosinusitis Clinical Trials

Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel

Start date: May 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of AdvaCoat® sinus gel, a nasal/sinus dressing, for adhesion prevention following endoscopic ethmoid sinus surgery. Subjects were randomized to receive AdvaCoat applied to the right or left middle meatus tissues and Merogel applied to the middle meatus tissues on the opposite side.

NCT ID: NCT00534079 Completed - Cystic Fibrosis Clinical Trials

Nasal Inhalation of Pulmozyme in Patients With Cystic Fibrosis and Chronic Rhinosinusitis

Start date: September 2007
Phase: Phase 3
Study type: Interventional

Rhinosinusitis disorders are often associated with Cystic Fibrosis. They can restrict quality of life enormously and give cause to repeated ENT surgery. The basic defect in CF is a dysfunction of chloride channels in exocrine glands, leading to retention of secretions and consecutive chronic inflammation with bacterial superinfections. The prospective placebo controlled cross-over study aims at the evaluation of a nasally inhalation of Pulmozyme with respect to mucus retention and resulting inflammation.

NCT ID: NCT00441246 Completed - Clinical trials for Acute Respiratory Infection

Phase 4 Study - Mucinex D as Adjunct Therapy

Start date: February 2007
Phase: Phase 4
Study type: Interventional

The objective of the study is to evaluate the safety and efficacy of Mucinex D tablets in providing symptom relief when administered as an adjunct to antibiotic therapy in patients with acute respiratory infection.

NCT ID: NCT00292851 Completed - Rhinosinusitis Clinical Trials

Blown Nasal Secretion Measurements in Rhinosinusitis: Repeatability and Validity Compared to Nasal Lavage

Start date: July 2004
Phase: N/A
Study type: Observational

To process blown nasal secretions from subjects with rhinosinusitis and to obtain a specimen by nasal lavage. To investigate the reliability and validity of the measurements we will determine their repeatability and compare them with those of nasal lavage in the same subjects.