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Rhinitis clinical trials

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NCT ID: NCT03097432 Completed - Clinical trials for Seasonal Allergic Rhinitis

Non-interventional Study to Assess the Tolerability, the Safety Profile and the Adherence of Different Up-dosing Schemes for a Sublingual Immunotherapy Treatment

Start date: October 20, 2016
Phase: N/A
Study type: Observational

This prospective open multi-centre non-interventional study initiated to document the up-dosing period of children and adults with allergic rhinoconjunctivitis and/or allergic asthma treated with a SLIT containing purified, aqueous extracts of birch, alder, and hazel pollen. The following up-dosing schemes are freely selectable: scheme A consists of an up-dosing period of 12 days at the patient´s home using the standardized pollen extract in three different solution strengths to reach the maximum dose; scheme B is performed only with the highest solution strength at the physician's office within 2 hours; and the new scheme C which is a regimen for initiation at the physician`s office and continuation at the patient`s home also exclusively using the highest solution strength and takes 4 days. Data are documented by physicians and in patients´ diaries.

NCT ID: NCT03075917 Recruiting - Allergic Rhinitis Clinical Trials

Validation of an Allergic Rhinitis Control Test in Children

ARCTEnfants
Start date: May 4, 2017
Phase: N/A
Study type: Interventional

Allergic rhinitis is a common condition that affects adults as well as children and adolescents, often with impaired quality of life. Patients often report a poor level of satisfaction with the effectiveness of their treatment and are always looking for more drug combinations to improve their symptom. Several tools exist for assessing control of allergic rhinitis, but none has been validated in teenagers or in children. A study conducted in 2008, resulted in the validation of a self-administered control test of allergic rhinitis (ARCT) in patients from 12 years of age. We propose to adapt ARCT adult to pediatric population from 5 to 11 years old.

NCT ID: NCT03070288 Completed - Allergic Rhinitis Clinical Trials

RGB(Red- Green-Blue) Measurement of the Nasal Mucosal Image

Start date: February 1, 2018
Phase:
Study type: Observational

The aim of this study was to evaluate the color values of the nasal mucosa, which is easily assessable by a direct, non-invasive, objective photographic measurement, for the purpose of presenting a diagnostic objective parameter of allergic rhinitis (AR). All patients and controls were examined by the same 4 mm 0⁰endoscope and light source, and all endoscopic photographs of the septum and both inferior turbinates were taken. Adobe Photoshop Elements 7.0 program was used to measure the numerical values of the red-green-blue (RGB) color components in endoscopic photographs of the nasal mucosa on the septum and inferior turbinates.

NCT ID: NCT03039816 Completed - Allergic Rhinitis Clinical Trials

Cellulose Powder Against Grass Pollen Allergic Rhinitis

CPARGPDBPC
Start date: May 2013
Phase: Phase 2/Phase 3
Study type: Interventional

Background: A nasally applied cellulose powder is increasingly used in many countries as a remedy for allergic rhinitis. In 2009, a 4-week study in birch pollen-allergic children showed a reduction in nasal symptoms. The best effect occurred on days with lower pollen counts. The present study in grass pollen-allergic adults used the same basic design. Methods: In May 2013, a double-blind, placebo-controlled study was conducted in 108 patients with allergic rhinitis due to grass pollen (18-40 years of age). SMS on mobile phones were used as reminders of treatment and reporting of symptom scores.

NCT ID: NCT03038971 Terminated - Allergic Rhinitis Clinical Trials

Study Evaluating Safety of Ragweed Mix Given by Intralymphatic Node Injections

Start date: March 30, 2017
Phase: Phase 1
Study type: Interventional

A safety study conducted on subjects ≥16 years old evaluating the safety of 4 intralymphatic injections of 2 different dose levels of the investigational short and tall ragweed product. Biomarkers will be assessed at baseline and at multiple time points post-treatment.

NCT ID: NCT03033290 Recruiting - Allergic Rhinitis Clinical Trials

Traditional Chinese Medicine on Gut Microbiota and Allergic Diseases

Start date: January 10, 2018
Phase: Phase 3
Study type: Interventional

Allergic rhinitis is an importance disease in Taiwan with its high incidence about 20-30% and gradually increased annually. However, symptom relapse still bothered the majority of patients though there were certain advances in western medicine. In addition, side effects of western medicine, such as lethargy, mouth dryness were noted. Traditional Chinese medicine, especially qi-tonifying regimen has been used and proved benefit to the allergic diseases by many researchers.This study will provide the evidences of gut microbiota changes and immune-modulatory effects of BZYQT for the treatment of allergic rhinitis.

NCT ID: NCT03014661 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Untersuchung Zur Erfassung Und Kontrolle Der Lebensqualität Unter Einer Therapie Mit Pollinex Quattro Bei Heuschnupfen

Start date: June 2015
Phase: N/A
Study type: Observational

Questionnaire to measure and control the quality of life of patients with hay fever who are treated or were treated with Pollinex quattro

NCT ID: NCT03009136 Recruiting - Clinical trials for Perennial Allergic Rhinitis

Efficacy and Safety of So-Cheong-Ryong-Tang on Perennial Allergic Rhinitis

Start date: December 31, 2016
Phase: Phase 3
Study type: Interventional

The aim of this study is to investigate the short and long term efficacy and the safety of SCRT treatment for PAR

NCT ID: NCT03004131 Completed - Clinical trials for Seasonal Allergic Rhinitis

MP-AzeFlu Allergen Chamber - Onset of Action Study

Start date: January 7, 2017
Phase: Phase 4
Study type: Interventional

This study is to assess the onset of action of fixed drug combination of azelastine hydrochloride and fluticasone propionate nasal spray (MP-AzeFlu) in treating the nasal symptoms of seasonal allergic rhinitis (SAR) induced by an allergen challenge in an Environmental Exposure Chamber (EEC).

NCT ID: NCT02988778 Withdrawn - Clinical trials for Rhinitis, Allergic, Perennial

Clinical Study, Non Inferiority Between Noex® 50µg Versus Busonid® 50µg in Treatment of Allergic Rhinitis

RINEX50
Start date: October 8, 2019
Phase: Phase 3
Study type: Interventional

This study is to evaluate non inferiority of Eurofarma budesonide nasal spray x referral Astrazeneca budesonide. Half patients will receive Eurofarma medication and half patients will receive Astrazeneca medication. There is no placebo group.