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Rhinitis clinical trials

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NCT ID: NCT03882047 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Mometasone Furoate Aqueous (MK-0887/SCH 032088) Nasal Spray vs Placebo and FLONASE® in Seasonal Allergic Rhinitis Patients (I94-001)

Start date: August 11, 1994
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of mometasone furoate (SCH 32088) aqueous nasal spray 200 mcg once daily compared to placebo once daily in the treatment of participants with seasonal allergic rhinitis. Flonase (fluticasone propionate) nasal spray 200 mcg once daily has been chosen as the active control for this study.

NCT ID: NCT03879772 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Dose-Ranging Study of Mometasone Furoate (MK-0887/SCH 032088) Nasal Spray in the Treatment of Children (Ages 6-11) With Seasonal Allergic Rhinitis (C95-161)

Start date: March 12, 1996
Phase: Phase 3
Study type: Interventional

The purpose of this study was to identify the lowest dosage of mometasone furoate nasal spray (MFNS) that provided adequate efficacy with an acceptable safety profile for children (ages 6-11) with seasonal allergic rhinitis (SAR). The MFNS dose levels of 25, 100, and 200 mcg QD were compared with beclomethasone dipropionate (BDP), as an active control, and placebo.

NCT ID: NCT03872219 Not yet recruiting - Allergic Rhinitis Clinical Trials

Biodiversity Intervention and Atopic Sensitization

PREVALL
Start date: March 25, 2019
Phase: N/A
Study type: Interventional

Children will receive biodiversity intervention or placebo. The proof of concept trial is double blind. Intervention will start at the age of 2 months and last 10 months. Children will be randomized to arms. IgE sensitization is the primary outcome.

NCT ID: NCT03861559 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Onset of Action of Mometasone Furoate (MK-0887/SCH 032088) Nasal Spray Compared With Placebo in Seasonal Allergic Rhinitis (C93-184)

Start date: March 30, 1994
Phase: Phase 3
Study type: Interventional

This study investigated the onset of symptom relief following initiation of treatment with mometasone furoate (MK-0887/SCH 032088) 200 mcg administered once daily compared with placebo for 14 days.

NCT ID: NCT03855228 Completed - Rhinitis, Allergic Clinical Trials

Safety and Efficacy of Mometasone Furoate Nasal Spray With the Addition of Loratadine Versus Placebo in Participants With Seasonal Allergic Rhinitis (C94-145)

Start date: March 1, 1995
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of mometasone furoate nasal spray (MFNS) with the addition of loratadine vs MFNS alone, loratadine alone, or placebo, in the treatment of patients with seasonal allergic rhinitis.

NCT ID: NCT03855189 Completed - Clinical trials for Seasonal Allergic Rhinitis

Safety and Efficacy of Mometasone Furoate (SCH 032088) vs Beclomethasone Dipropionate or Placebo in Seasonal Allergic Rhinitis (C93-013)

Start date: August 23, 1993
Phase: Phase 3
Study type: Interventional

The objectives of this study are to determine the safety and efficacy in seasonal allergic rhinitis of a four-week course of mometasone furoate compared to beclomethasone dipropionate or placebo.

NCT ID: NCT03821077 Completed - Rhinoconjunctivitis Clinical Trials

Study to Evaluate the Efficacy and Safety of "Allergovac Poliplus" in Polysensitized Patients With Allergic Rhinitis/Rhinoconjunctivitis, With or Without Asthma

ARES
Start date: August 30, 2018
Phase:
Study type: Observational

This is an observational prospective multicenter clinical study, to evaluate the efficacy and safety of the treatment with Allergovac Poliplus subcutaneous immunotherapy (SCIT) with a mixture of 2 allergenic extracts (pollens or mites), in polymerized-depot formulation, administered in its different available allergenic extracts mixtures (2 pollens or 2 mites), and in one of the 2 recommended administration schedules (1 Day or Rapid).

NCT ID: NCT03820154 Not yet recruiting - Allergic Rhinitis Clinical Trials

Diagnostic Equivalence of the Skin Prick Test Tape vs. Conventional Skin PrickTest

SPTTapeD1
Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Testing of a new ready-to-use Tape in comparison to the currently used skin prick test for the diagnosis of allergies. Assessment of clinical equivalence of the SPT Tape for representative common inhalant allergens to conventional SPT in terms of wheal reaction positivity and overall safety. Tests are performed in patients who have a medical history of relevant allergic rhinitis to any of the tested allergens.

NCT ID: NCT03791489 Completed - Chronic Rhinitis Clinical Trials

Multi-Treatment PNN Modulation for Chronic Rhinitis

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

Feasibility of treatment at multiple sites with the ClariFix cryoablation device for treatment of chronic rhinitis

NCT ID: NCT03776773 Completed - Allergic Rhinitis Clinical Trials

Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR Study

POLLAR
Start date: April 8, 2019
Phase: N/A
Study type: Interventional

It has been demonstrated that allergic rhinitis (AR) reduces sleep quality by some components such as nasal obstruction. Pollution and allergen exposure worsening AR, sleep quality is deteriorated. Sleep is associated to physical and mental health, alterations in sleep could explain the link between AR and work productivity diminution, impairment in daily activities or emotional problems. However, interactions between air pollution, sleep and allergic diseases are insufficiently understood. The main objective of this study is to determine the impact of pollution and pollens on sleep parameters.