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Rhinitis, Vasomotor clinical trials

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NCT ID: NCT05348148 Recruiting - Allergic Rhinitis Clinical Trials

Comparison of the Effects for Lightening the Shiners Among Different Treatments for Rhinitis

Start date: June 16, 2020
Phase: N/A
Study type: Interventional

Background: Shiners are caused when blood and other fluids accumulate in the infraorbital groove. It develops resulting from lots of problems. In patient with rhinitis, either allergic rhinitis or non-allergic rhinitis, shiners are believed to be caused by venous stasis resulting from nasal congestion. This study is aiming that comparison of the effectiveness of treatment of rhinitis (either allergic rhinitis or non-allergic rhinitis) to lighten not only the rhinitis but also the shiners. Randomized control studies. Design: The investigators will recruit children (6-12 y/0), adolescent (13-18 y/o), or adults (19-65 y/o) with either allergic rhinitis or non-allergic rhinitis, and patients will be randomly assigned to groups (oral antihistamine, combined nasal corticosteroids with oral antihistamine, combined nasal corticosteroids with oral antihistamine plus nasal decongestant, combined nasal corticosteroids with oral antihistamine plus nasal irrigation, combined oral antihistamine with nasal irrigation, or nasal antihistamine only). Digital image will be recorded and analyzed to compare the change of shiners between before and after treatment for rhinitis. The clinical data were collected including patient's data, history, laboratory data, Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ), Adolescent Rhinoconjunctivitis Quality of Life Questionnaire (AdolRQLQ), or mini Rhinoconjunctivitis Quality of Life Questionnaire (mini-RQLQ), and medications. The primary outcome is to answer whether the levels of shiners can be alleviated by using therapies in patient with rhinitis. And the secondary outcome is to figure out which therapies work most effectively. Keywords: allergic rhinitis, vasomotor rhinitis, shiners, nasal corticosteroids

NCT ID: NCT02338102 Completed - Nasal Obstruction Clinical Trials

Nasal Saline Irrigation After Radiation Therapy for Oropharyngeal Cancer

Start date: January 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to learn whether nasal saline irrigation is beneficial to patients undergoing radiation therapy for oropharyngeal cancer.

NCT ID: NCT01509209 Completed - Vasomotor Rhinitis Clinical Trials

Efficacy/Safety of Pseudoephedrine Plus Levocetirizine Versus Placebo in Patients With Vasomotor Rhinitis

Start date: May 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate efficacy and safety of Cossac L tablet in the treatment of vasomotor rhinitis

NCT ID: NCT00979615 Completed - Vasomotor Rhinitis Clinical Trials

Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis

Start date: September 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to examine safety and efficacy of Patanase and Astelin in treating the symptoms of non-allergic vasomotor rhinitis (VMR).

NCT ID: NCT00976209 Completed - Clinical trials for Seasonal Allergic Rhinitis

Consumer Preference Study of Two Formulations of Phenylephrine Hydrochloride (Study CL2008-15)(P07530)(COMPLETED)

Start date: August 2009
Phase: Phase 3
Study type: Interventional

This is a randomized, two-way crossover, multicenter study evaluating the consumer preference of Phenylephrine Extended Release Tablets, 30 mg to be taken as one tablet every 12 hours, or Phenylephrine Immediate Release Tablets, 10 mg to be taken as one tablet every 4 hours in subjects with at least mild allergic rhinitis and nasal congestion. Approximately 250 participants will complete a questionnaire after taking one test product for 3 days followed by a 3 day (± 1 day) washout period; and then taking the alternate test product for 3 days. Analysis of which product the consumer preferred, if any, and which product was more convenient, if any, will be evaluated.

NCT ID: NCT00745849 Completed - Vasomotor Rhinitis Clinical Trials

Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled Trial

Start date: June 2005
Phase: N/A
Study type: Interventional

The purpose of this study was to see if high dose esomeprazole (40mg bid) was effective in treating non-allergic rhinitis

NCT ID: NCT00682162 Completed - Acupuncture Clinical Trials

Impact of Acupuncture on Vasomotor Rhinitis

Start date: January 1998
Phase: Phase 3
Study type: Interventional

Chronic rhinitis without an allergic or infectious aetiology (vasomotor rhinitis) is a common disease for which there are only poor therapeutic treatment options. The current placebo controlled partially double blinded pilot study evaluated the effects of acupuncture on the symptoms of vasomotor rhinitis.

NCT ID: NCT00415493 Completed - Vasomotor Rhinitis Clinical Trials

Nasal Physiologic Reactivity of Nonallergic Rhinitics to Cold Air Provocation

Start date: December 2006
Phase: N/A
Study type: Interventional

This study seeks to compare patients with vasomotor rhinitis ("perennial nonallergic rhinitis," "idiopathic rhinitis") with normal controls with respect to their nasal physiologic reactivity to cold air challenge. Ten vasomotor rhinitis (VMR) patients with nasal symptoms triggered predominantly by cold air, four VMR patients with symptoms triggered predominantly by chemicals, and ten nonallergic, non-rhinitic control subjects will be studied.

NCT ID: NCT00118703 Completed - Vasomotor Rhinitis Clinical Trials

Once-Daily Investigational Nasal Spray In Adults And Adolescents With Vasomotor Rhinitis

Start date: July 2005
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to compare the efficacy and safety of GW685698X 100mcg once daily (QD) aqueous nasal spray with vehicle placebo nasal spray in adult and adolescent subjects (12 years of age and older) with vasomotor rhinitis (VMR).

NCT ID: NCT00117325 Completed - Rhinitis, Vasomotor Clinical Trials

Study Of Adults And Adolescents With Vasomotor Rhinitis

Start date: July 11, 2005
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to compare the efficacy and safety of GW685698X 100mcg once daily (QD) aqueous nasal spray with vehicle placebo nasal spray in adult and adolescent subjects (12 years of age and older) with vasomotor rhinitis (VMR).