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Rhinitis, Allergic, Seasonal clinical trials

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NCT ID: NCT02256553 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Safety Study of MK-3641 and MK-7243 Co-administered in Adult Participants With Ragweed and Grass Pollen Induced Allergic Rhinitis (P08607, MK-3641-006)

Start date: October 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of MK-3641 (short ragweed [Ambrosia artemisiifolia] extract, SCH 039641, RAGWITEK®) sublingual tablets and MK-7243 (Timothy grass [Phleum pratense] extract, SCH 697243, GRASTEK®) sublingual tablets co-administered in participants 18 through 65 years of age with both ragweed- and grass polled-induced allergic rhinitis, with or without conjunctivitis and with or without asthma. The primary endpoint is the percentage of participants who experience at least one event of local swelling after co-administration of MK-3641 and MK-7243 sublingual tablets.

NCT ID: NCT02249663 Recruiting - Clinical trials for Seasonal Allergic Rhinitis

Clinical Equivalence of Azelastine Hydrochloride and Fluticasone Propionate, 137/50 mcg Nasal Spray to Dymista™

Start date: August 2014
Phase: Phase 3
Study type: Interventional

To evaluate the therapeutic equivalence of a test formulation of Azelastine hydrochloride and Fluticasone propionate Nasal Spray to the reference listed drug, Dymista™ Nasal Spray in the relief of the signs and symptoms of Seasonal Allergic Rhinitis.

NCT ID: NCT02246920 Terminated - Clinical trials for Seasonal Allergic Rhinitis

Clinical Equivalence Study of Fluticasone Propionate Nasal Spray, 50 mcg/Actuation vs. Flonase in Allergic Rhinitis Patients

Start date: March 1, 2014
Phase: Phase 3
Study type: Interventional

This double-blind, randomized, placebo-controlled, parallel group, multi-site study has been designed to compare the safety and efficacy of a generic Fluticasone propionate Nasal Spray, 50 mcg (Teva Pharmaceuticals USA) to the FDA Reference Listed Drug, Flonase® (fluticasone propionate) 50 mcg nasal spray (GlaxoSmithKline), in the relief of the signs and symptoms of Seasonal Allergic Rhinitis. Additionally, both the test and reference formulations will be tested for superiority against a placebo nasal spray.

NCT ID: NCT02245360 Completed - Clinical trials for Seasonal Allergic Rhinitis

Study Immunology and Safety of 60-day Treatment of SQ Grass SLIT (Sublingual Immunotherapy)-Tablet in Adult Subjects With Grass Pollen-induced Allergic Rhinoconjunctivitis

Start date: October 2014
Phase: Phase 3
Study type: Interventional

To investigate the immunologic effects and safety of 60-day treatment of the Standardized Quality units (SQ) grass Sublingual immunotherapy (SLIT)-tablet in adult subjects with grass pollen-induced allergic rhinoconjunctivitis in a double-blind, placebo-controlled study.

NCT ID: NCT02230696 Completed - Clinical trials for Seasonal Allergic Rhinitis

Comparative Safety and Efficacy of Two Steroid Treatments in the Relief of the Symptoms of Seasonal Allergic Rhinitis

Start date: August 2014
Phase: Phase 3
Study type: Interventional

To compare safety and efficacy of Perrigo's steroid drug product compared with an FDA approved steroid drug product in the treatment of subjects with seasonal allergic rhinitis.

NCT ID: NCT02161107 Completed - Asthma Clinical Trials

Study of Grass-SPIRE in Subjects With Grass Allergies and Asthma

Start date: April 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether it is safe to administer Grass-SPIRE to subjects suffering from both grass allergy and asthma

NCT ID: NCT02156791 Completed - Hay Fever Clinical Trials

Safety, Clinical Tolerability and Immunogenicity of Increasing Doses of gpASIT+TM

Start date: August 2013
Phase: Phase 2
Study type: Interventional

gpASIT+TM product is based on highly purified allergen fragments obtained from grass pollen. The purpose of this clinical trial is to confirm the safety, clinical tolerability and immunogenicity of increasing doses of gpASIT+TM administered subcutaneously to patients with grass pollen-induced allergic rhinoconjunctivitis, and to determine the maximal tolerated dose of gpASIT+TM .

NCT ID: NCT02155881 Completed - Clinical trials for Seasonal Allergic Rhinitis

Efficacy and Safety of Ciclesonide Nasal Spray in Participants With Seasonal Allergic Rhinitis (SAR) in Russia

Start date: August 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to explore the efficacy and safety of Ciclesonide Nasal Spray 200 mcg once daily in the treatment of seasonal allergic rhinitis (SAR) in Russian participants.

NCT ID: NCT02146300 Not yet recruiting - Clinical trials for Birch Pollen Allergy

Effect of the Nasal Provocation on the Breathing Style

Start date: March 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to find out how the provocation of the nose changes breathing style (specifically, frequency and tidal volume changes)

NCT ID: NCT02143583 Completed - Clinical trials for Birch Pollen Allergy

Follow-up of Study AN004T to Assess the Persistence of AllerT Efficacy During the 2nd to 4th Season After Treatment

Start date: February 2014
Phase: Phase 2
Study type: Observational

Study aiming to evaluate the efficacy of a 2-month pre-seasonal treatment with an AllerT 50 µg or 100 µg maintenance dose administered in previous study AN004T in reducing symptoms of allergic rhinoconjunctivitis during the 2nd following birch pollen season.