The Cartilage and Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis Clinical Trial

Official title:

The Effect of Ultrasonographic Cartilage Thickness and Quadriceps/Hamstring Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05999266
• Other study ID #: 15082023
• Status: Completed
• Start date: September 28, 2023
• Est. completion date: November 12, 2023

Study information

• Verified date: November 2023
• Source: Sisli Hamidiye Etfal Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The knee pain status of the patients who are followed in the rheumatology special branch of the Physical Medicine and Rehabilitation Outpatient Clinic and who meet the inclusion criteria will be questioned. In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest. The physician who performed the ultrasonographic measurements of the knee pain status of the patients does not know.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 130
• Est. completion date: November 12, 2023
• Est. primary completion date: November 10, 2023
• Gender: Female
• Age group: 30 Years to 50 Years

Eligibility

Inclusion Criteria:

• Rheumatoid Arthritis > Diagnosed for 1 year

• -Female gender

• -The patient has been in remission or low disease activity for at least 3 months

• -Be able to ambulatory

• -No significant deformity in the lower extremity joints

Exclusion Criteria:

• Patient with active arthritis or high disease activity

• - Significant deformity of the lower extremity joints and inability to ambulate

• -Pregnant patient

• - Presence of malignancy

• - Patient with a severe psychiatric disorder and difficulty in cooperation

• - Presence of cardiovascular and pulmonary comorbidities that will prevent exercise

• -Male gender

Related Conditions & MeSH terms

• Arthritis
• Arthritis, Rheumatoid
• Cartilage Degeneration
• Knee Pain Chronic
• Muscle Loss
• Rheumatoid Arthritis

Intervention

Diagnostic Test:
• Ultrasonographic Measurements
In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest.

Locations

Country	Name	City	State
Turkey	University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Sisli Hamidiye Etfal Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Ultrasonographic Cartilage Thickness Measurement	Tibial cartilage thickness will be visualized by ultrasound with the knee held in 30 degrees of flexion, and 3 measurements will be taken from the medial, lateral and midline.	through study completion, an average of 1 month
Primary	Ultrasonographic Muscle Measurement Thickness Measurement	The quadriceps muscle thickness will be measured by determining the midpoint between the SIAS and the patella while the patient is lying in the supine position. Hamstring muscle thickness will be measured at the intersection of a line drawn at 60% distal between the greater trochanter and the outer femoral condyle, and at the midline of the popliteal fossa, with the patient lying on the prone. These 2 measurements will be proportional to each other.	through study completion, an average of 1 month