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Iguratimod Combined With Tofacitinib in the Treatment of Rheumatoid Arthritis

Rheumatoid Arthritis Clinical Trial

Official title:
Efficacy and Safety of Iguratimod Combined With Tofacitinib in the Treatment of csDMARD-IR Patients With Active Moderate-to-severe Rheumatoid Arthritis： a Prospective, Randomized, Controlled, Multicenter Study

Clinical Trial Summary

The purpose of this study is to assess the efficacy and safety of Iguratimod combined with Tofacitinib in the treatment of csDMARD-IR patients with active moderate-to-severe rheumatoid arthritis

Clinical Trial Description

After being informed about the study and potential risks, all patients giving written informed consent will undergo a 1-week screening period to determine eligibility for study entry. At week 0, patients who meet the eligibility requirements will be randomized in a double-blind manner (participant and investigator) in a 1:1 ratio to Iguratimod (25mg, twice daily) combined with Tofacitinib (5mg, twice daily) or placebo (25mg, twice daily) combined with Tofacitinib (5mg, twice daily). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05803135
Study type Interventional
Source Nanfang Hospital of Southern Medical University
Contact
Status Not yet recruiting
Phase Phase 4
Start date March 31, 2023
Completion date December 30, 2025
View Details
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