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Efficacy and Safety of TwHF and MTX in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis Clinical Trial

Official title:
A 24-Week, Multicenter ,Double Blind, Randomized Study to Determine the Effects and Security of TwHF and MTX Treating Rheumatoid Arthritis

Clinical Trial Summary

Rheumatoid Arthritis (RA) is an autoimmune disease that results in a chronic inflammatory disorder that may affect many synovial joints, and may cause serious disability. It has been confirmed that Tripterygium Wilfordii has effects of anti-inflammatory, immunosuppressive and cartilage protection. This is a multicenter ,double Blind, randomized study to evaluated the efficacy and safety of Tripterygium Wilfordii in treating of patients with rheumatoid arthritis (RA) and establish a prediction model for Tripterygium Wilfordii response of rheumatoid arthritis (RA).

Clinical Trial Description

Two arms were included in this study. Active Comparator: treatment of MTX Patients were treated with methotrexate (MTX)and Tripterygium wilfordii Hook F（TwHF）placebo.Experimental: treatment of TwHF Patients were treated with methotrexate (MTX) and Tripterygium wilfordii Hook F（TwHF). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03324412
Study type Interventional
Source Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Contact Jiang Quan, MD
Phone 010-88001060
Email doctor@126.com
Status Not yet recruiting
Phase Phase 2/Phase 3
Start date October 28, 2017
Completion date September 30, 2019
View Details
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