Rheumatoid Arthritis Clinical Trial
Official title:
A Phase 2a, 4-Week Double-Blind, Proof-of-Concept Efficacy and Safety Study of CC-292 Versus Placebo as Co-therapy With Methotrexate in Active Rheumatoid Arthritis
CC-292 is an oral agent that is under clinical development for the treatment of rheumatoid
arthritis an autoimmune inflammatory disorder.
This study will test the clinical effectiveness and safety of an orally (PO) administered
dose of CC-292 compared to placebo in US female patients currently on background Methotrexate
(MTX) with active Rheumatoid Arthritis (RA
This is a Phase 2a, multicenter, randomized, double-blind, placebo-controlled,
proof-of-concept study to determine the efficacy and safety of CC-292 (375 mg PO daily) on a
stable background of MTX therapy in female subjects with active RA.
Approximately 80 female subjects with active RA will be randomized 1:1 into two dose groups:
active CC-292 (375 mg PO daily) or identically-appearing placebo capsules for 4 weeks
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