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Clinical Trial Summary

It is known from the COMET-trial that patients who start Enbrel treatment early have a great chance of reaching clinical remission and radiographic nonprogression. It is still unclear, however, how many patients with early arthritis achieve remission and radiographic nonprogression under the conditions of routine rheumatologic care and the local recommendations of Enbrel treatment (pre-treatment of at least 2 DMARDs, one of them MTX).

Therefore, no robust x-ray data are available to show/demonstrate

- the average extent of x-ray damage in routine patients on Enbrel outside clinical studies.

- if the outstanding effect on structural damage of Enbrel can be reproduced in routine practice.

- that the 'Silent Progressor' is an issue relevant not only in clinical trials, but also for day-to-day decision making.

- the optimal onset of Enbrel treatment in the course of the disease to prevent radiographic damage


Clinical Trial Description

Non-interventional study: subjects to be selected according to the usual clinical practice of their physician ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01623752
Study type Observational
Source Pfizer
Contact
Status Completed
Phase
Start date February 2012
Completion date March 2018

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