Rheumatoid Arthritis Clinical Trial
Official title:
The Relation Between Dedicated Extremity MRI Synovitis and Structural Deterioration Radiographic in Patients With Rheumatoid Arthritis in Clinical Remission.Preliminary Study
The major aim of treatment for rheumatoid arthritis is remission. Nevertheless, structural
radiographic progression is observed in 15 to 20% of patient getting remission. Numerous
definitions of the remission proposed by literature remain imperfect.
Recently ultrasonography and MRI seem to be helpful in diagnosis and follow-up of rheumatoid
arthritis.
Studies in patients with clinical remission are reporting 75 to 90% of persistent MRI and
ultrasonography synovitis, 45% of cases with synovial activity.
To our knowledge, in such case few studies showed correlation between persistent imaging
synovitis and structural radiographic progression.
On the other hand, no studies with extremity dedicated RMI in patients with remission are
reported.
In this preliminary study, the investigators propose to evaluate in patients with rheumatoid
arthritis remission and persistent dedicated MRI synovitis the structural radiographic
progression at one year.
n/a
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Screening
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