Rheumatoid Arthritis Clinical Trial
— RA&ExOfficial title:
Evaluation of the Effect of Exercise on Disease Activity and Immune Parameters in Persons With Rheumatoid Arthritis
Verified date | August 2023 |
Source | University of Nebraska |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study will evaluate the effect of exercise on the number of swollen and tender joints associated with rheumatoid arthritis after a 12 week exercise program of treadmill walking and weightlifting.
Status | Completed |
Enrollment | 55 |
Est. completion date | November 1, 2006 |
Est. primary completion date | April 1, 2006 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 19 Years to 65 Years |
Eligibility | Inclusion Criteria: - a diagnosis of RA according to the ACR 1989 Criteria at least 6 months prior to enrollment in the study, but not longer than 12 years - age 19 to 65 years old - stable regimen of medication for 2 months with less than 10 mg/day of oral corticosteroids - currently exercise < 2x/week for less than 30 minutes at less than 60% of his/her age predicted maximum heart rate - Subjects must pass the Physical Activity Readiness Scale Questionnaire (PAR-Q) Exclusion Criteria: - other serious health problems - intra-articular injection within 6 weeks - total joint replacement of the large joints - use of beta-blockers - inability to complete the submaximal exercise test |
Country | Name | City | State |
---|---|---|---|
United States | Physical Activity Lab, University of Nebraska Omaha | Omaha | Nebraska |
Lead Sponsor | Collaborator |
---|---|
University of Nebraska | Arthritis Foundation, Nebraska Chapter Arthritis Foundation |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Swollen Joint Count | 12 Weeks | ||
Primary | Tender Joint Count | 12 Weeks | ||
Secondary | Pain (visual Analog Scale) | 12 Weeks | ||
Secondary | Modified-Health Assessment Questionnaire | 12 Weeks | ||
Secondary | Estimated Aerobic Capacity (VO2max) | 12 weeks | ||
Secondary | SF-36 | 12 Weeks | ||
Secondary | Patient Global Assessment | 12 Weeks | ||
Secondary | Practitioner Global Assessment | 12 Weeks | ||
Secondary | Timed-Stands Test | 12 Weeks | ||
Secondary | 50 Foot Walk Test | 12 Weeks |
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