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NCT03935074 Clinical Trial

Superselective Intra-arterial Chemotherapy Treatment for Retinoblastoma- 5 Year Results From Turkey

Retinoblastoma Clinical Trial

Official title:
Superselective Intra-arterial Chemotherapy Treatment for Retinoblastoma- 5 Year Results From Turkey

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03935074
Other study ID # 10136532
Secondary ID
Status Completed
Phase
First received
Last updated
Start date August 30, 2016
Est. completion date November 30, 2016

Study information
Verified date May 2019
Source Istanbul University-Cerrahpasa
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Retrospective review of 5-year long term outcomes of superselective intra-arterial chemotherapy treatment in retinoblastoma in a single institute.

The treatment outcomes, globe salvage rates and complications of superselective intra-arterial chemotherapy both for treating naive patients (primary treatment group) and for patients who received systemic chemotherapy previously (secondary treatment group) were evaluated.

Recruitment information / eligibility
Status Completed
Enrollment 30
Est. completion date November 30, 2016
Est. primary completion date November 30, 2016
Accepts healthy volunteers
Gender All
Age group 5 Months to 7 Years
Eligibility Inclusion Criteria:

- patients diagnosed with unilateral/bilateral retinoblastoma

Exclusion Criteria:

- patients with trilateral retinoblastoma

- extraoculer involvement

- patients with blood dyscrasias, bleeding and clotting disorders

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• intra-arterial administration of melphalan

Locations
Country Name City State
Turkey Istanbul University Cerrahpasa School of Medicine Ophthalmology Department Istanbul

Sponsors (1)
Lead Sponsor Collaborator
Istanbul University-Cerrahpasa

Country where clinical trial is conducted

Turkey, 

References & Publications (1)

Saglam M, Sarici A, Anagnostakou V, Yildiz B, Kocer N, Islak C, Kizilkilic O. An alternative technique of the superselective catheterization of the ophthalmic artery for intra-arterial chemotherapy of the retinoblastoma: retrograde approach through the posterior communicating artery to the ophthalmic artery. Neuroradiology. 2014 Sep;56(9):751-4. doi: 10.1007/s00234-014-1388-1. Epub 2014 Jun 10. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary globe salvage globe salvage rate after superselective intra-arterial chemotherapy treatment for retinoblastoma 2-5 years
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