Efficacy Study of Lucentis in the Treatment of Retinoblastoma

Status Recruiting

Clinical Trial Summary

This study will evaluate the clinical efficacy of intravitreal injections of Ranibizumab (Lucentis) together with chemotherapy in the treatment of Retinoblastoma as compared to chemotherapy alone.

Clinical Trial Description

This study will be a phase II open label interventional case series. Patients with retinoblastoma will be randomized to receive chemotherapy with or without intravitreal ranibizumab at a dose of 0.5mg/0.05 ml. Patients will receive ranibizumab via a pars plana injection on a monthly basis for a total duration of therapy of 6 months. Patients will be followed for 24 months . ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Retinoblastoma

Clinical Trial Details

NCT number	NCT01899066
Study type	Interventional
Source	Sun Yat-sen University
Contact	Huasheng Yang, M.D, PHD
Phone	+8620-87331539
Email	yanghs64@126.com
Status	Recruiting
Phase	Phase 2
Start date	July 2013
Completion date	December 2015

View Details

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