Retinoblastoma Clinical Trial
Official title:
A Pilot Study of Intra-Ophthalmic Artery Topotecan Infusion for the Treatment of Retinoblastoma
This study will test if giving topotecan directly into the blood vessel of the eye will
improve the treatment of retinoblastoma. This method is referred to as "selective
intra-ophthalmic artery chemotherapy" (SIOAC).
The goals of this study are:
- To find out if topotecan is an effective treatment for retinoblastoma when delivered
directly to the ophthalmic artery (SIOAC delivery)
- To find out what kind of effects (good and bad) can be expected when topotecan is given
by SIOAC
- To assess visual pathway function before and after the study therapy
- To learn more about the pharmacology (how your body handles the drug) of topotecan when
delivered directly to the ophthalmic artery
n/a
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