Retrospective Natural History Study of Retinitis Pigmentosa — PHENOROD1

Retinitis Pigmentosa (RP) Clinical Trial

Official title:
Natural History Study of Retinitis Pigmentosa in Patient Carrying Pathogenic Mutations in RHO, PDE6A or PDE6B.

Status Active, not recruiting

Clinical Trial Summary

This is natural history study of rods and cones degenerations in patients with Retinitis Pigmentosa (RP) caused by pathogenic mutations in RHO, PDE6A or PDE6B gene mutations.

Clinical Trial Description

This is a retrospective, longitudinal, observational case history study to determine the natural history of rods and cones degeneration in patients diagnosed with RP caused by pathogenic mutations in genes with selective expression in rods: rhodopsin (RHO), phosphodiesterase 6A (PDE6A) or phosphodiesterase 6B (PDE6B). 113 participants will be enrolled in this study at the single center: CHNO-CIC Quinze-Vingt Paris in France. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03975543
Study type	Observational
Source	SparingVision
Contact
Status	Active, not recruiting
Phase
Start date	October 1, 2018
Completion date	September 30, 2021

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02320812` - Safety of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Retinitis Pigmentosa	Phase 1/Phase 2
Recruiting	`NCT04763369` - Investigation of Therapeutic Efficacy and Safety of UMSCs for the Management of Retinitis Pigmentosa (RP)	Phase 2
Completed	`NCT01543906` - Oral QLT091001 in Retinitis Pigmentosa (RP) Subjects With an Autosomal Dominant Mutation in Retinal Pigment Epithelial 65 Protein (RPE65)	Phase 1
Completed	`NCT02575430` - Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT	N/A