Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning

Retinal Vein Occlusion Clinical Trial

Official title:

Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02898480
• Other study ID #: RIK-DVA
• Status: Completed
• Phase: N/A
• Start date: September 2016
• Est. completion date: May 2017

Study information

• Verified date: November 2017
• Source: University of Aarhus
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury. It remains unknown whether this can be used in retinal vascular occlusive diseases. The purpose of the present study is to examine whether the autoregulation of retinal vessel diameters in normal persons change after remote ischemic conditioning.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: May 2017
• Est. primary completion date: November 14, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 35 Years

Eligibility

Inclusion Criteria:

• Normal persons

Exclusion Criteria:

• Present or previous eye disease

• Use of medications except anti-conceptive

• Epilepsy

• Pregnancy or lactation

Related Conditions & MeSH terms

• Retinal Artery Occlusion
• Retinal Vein Occlusion

Intervention

Procedure:
• Remote ischemic conditioning
Briefly reversible restricting of blood flow to upper limb in four cycles of 5 minutes of inflation at 200mm Hg followed by 5 minutes of deflation.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Aarhus

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Diameter change of retinal vessel		immediate