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Retinal Perforations clinical trials

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NCT ID: NCT05083650 Recruiting - Macular Holes Clinical Trials

Large Macular Hole Closure Rate With Amniotic Membrane Graft With and Without Limitorrhexis

Start date: March 10, 2021
Phase: N/A
Study type: Interventional

Patients with idiopathic macular holes (MHs) postoperative closure rates for large MHs (diameter > 550 μm) are disappointing and often require a second intervention, different techniques have been described with very variable success rates in different published studies, an efficient technique with good functional outcome has not been found.

NCT ID: NCT04957459 Recruiting - Macular Holes Clinical Trials

The Correlation of Preoperative Measurement Parameter on the Predicting of Visual Outcomes Among Patients With Idiopathic Macular Holes

Start date: January 1, 2020
Phase:
Study type: Observational

This study retrospectively analyzed the relationship between the preoperative optical coherence tomography(OCT) and optical coherence tomography angiography(OCTA) software related parameters of patients with idiopathic macular hole, the patient's own clinical data and the best corrected visual acuity (BCVA) for at least one month after surgery.

NCT ID: NCT04698226 Recruiting - Macular Holes Clinical Trials

ILM Peeling Versus Inverted Flap Technique for Treatment of Macular Hole: Near Visual Acuity Outcomes

Start date: January 5, 2021
Phase: N/A
Study type: Interventional

A prospective randomised study comparing the near visual acuity outcomes using Salzburg Reading Desk in pseudophakic patients with idiopathic full-thickness macular hole treated with pars plana vitrectomy with internal limiting membrane peeling versus inverted flap technique. The aim of the study is confirm or disprove the hypothesis, that the near visual acuity results of pars plana vitrectomy with inverted flap technique for idiopathic macular hole are not inferior to pars plana vitrectomy with complete internal limiting membrane peeling technique. Patients will be followed for 6 months after the operation and near best corrected visual acuity testing on Salzburg reading desk, distance best corrected visual acuity on ETDRS tables and microperimetry will be performed and compared between both groups. Also the macular hole closure rate and complication rate will be compared between both groups.

NCT ID: NCT04676256 Recruiting - Retinal Detachment Clinical Trials

Early VItrectomy in DENse Spontaneous Vitreous HEmorrhage

EVIDENSE
Start date: July 2, 2021
Phase: N/A
Study type: Interventional

The aim of the protocol is to compare the ocular outcomes after spontaneous vitreous hemorrhage treated with an early vitrectomy versus ultrasound monitoring with late vitrectomy. The hypothesis is that an early vitrectomy could decrease the rate of retinal detachment occurring after a spontaneous vitreous hemorrhage.

NCT ID: NCT04498624 Recruiting - Clinical trials for Full Thickness Macular Hole

Inverted Flap Versus Internal Limiting Membrane Peeling in Small Full Thickness Macular Holes

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

Primary outcome: difference of microperimetry retinal sensitivity after primary vitrectomy for idiopathic full thickness macular holes with inverted flap technique versus internal limiting membrane (ILM) peeling technique Secondary outcomes: difference of visual change after primary vitrectomy for idiopathic full thickness macular holes with inverted flap technique versus internal limiting membrane (ILM) peeling technique; difference in closure rate after primary vitrectomy for idiopathic full thickness macular holes with inverted flap technique versus internal limiting membrane (ILM) peeling technique

NCT ID: NCT04404296 Recruiting - Retinal Detachment Clinical Trials

Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter

HYPE
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Report efficiency and clinical outcomes using 25-gauge, bevel-tip, 20000 cut per minute vitrectomy probe among eyes with various vitreo-retinal diseases

NCT ID: NCT04135638 Recruiting - Macular Holes Clinical Trials

Inverted ILM-flap Techniques Variants for Macular Hole Surgery: Outcomes Comparison

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

To report closure rate, Best Corrected Visual Acuity (BCVA), Retinal Sensitivity (RS) and Fixation Stability (FS) of idiopathic Macular Holes (MH) randomized to Cover Group (CG) or Fill Group (FG) of the Inverted Internal Limiting Membrane (ILM) flap surgical procedure.

NCT ID: NCT04116892 Recruiting - Macular Holes Clinical Trials

Comparative Analysis of Large Macular Hole Surgeries

CAOLMHS
Start date: May 1, 2019
Phase: N/A
Study type: Interventional

This study compares the anatomical and visual outcomes in a large series of patients affected by idiopathic macular holes larger than 400 µm treated using pars plana vitrectomy and gas tamponade combined with internal limiting membrane (ILM) peeling or the inverted internal limiting membrane flap technique. A part of the participants will receive internal limiting membrane peeling,whil the other will receive the inverted internal limiting membrane flap technique.

NCT ID: NCT03888625 Recruiting - Macular Holes Clinical Trials

Compare the Healing Process of Idiopathic Macular Hole With Different Surgical Techniques

Start date: June 15, 2018
Phase: N/A
Study type: Interventional

To compare anatomic and functional results, and to evaluate postoperatively the healing process in 2 different techniques for the closure of the macular holes (MH)

NCT ID: NCT03799575 Recruiting - C11.768.740 Clinical Trials

Internal Limiting Membrane and Macular Hole

Start date: January 2, 2019
Phase:
Study type: Observational

Observational study of Internal Limiting Membrane peeled in macular Hole surgery and studied by Transmission electronic Microscopy (TEM) and Optical Coherence Tomography (OCT) findings in closed holes.