Retinal Perforation Clinical Trial
Official title:
Early Vitrectomy for Impending Macular Hole. Multicenter Clinical Trial
This study is designed to verify hypothesis that early vitrectomy may prevent impending macular hole from progression to full-thickness macular hole.
In a study conducted 15 years ago, the 'Vitrectomy for Prevention of Macular hole Study
Group' was not able to prove the benefits and advantages of vitrectomy for impending macular
hole; however, during the interim period, notable improvements have been achieved with
regard to diagnosis and efficacy of treatment.
Therefore, we designed this study to identify the effect of current vitreous surgery for
symptomatic impending macular hole.
Characteristics of this study is as below
- Multicenter, prospective clinical trial. (early surgical intervention vs.surgical
intervention when full-thickness macular hole occurs)
- Non-randomized study (decision was made by patients after full explanation)
- After 1 year follow up, functional change(visual acuity)and anatomical
change(development of full-thickness macular hole) would be evaluated
;
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment