High Resolution Optical Coherence Tomography

Status Recruiting

Clinical Trial Summary

Comparison of high-resolution optical coherence tomography (High-Res-OCT) to conventional imaging modalities for the diagnosis of eye diseases

Clinical Trial Description

The high resolution optical coherence tomography (High-Res-OCT) is an improvement of a non-invasive routinely used imaging technique, the optical coherence tomography (OCT), with a light-source capable of providing an increased axial resolution. The routinely used Spectral-Domain OCT has a center wavelength of 880 nm and a spectral bandwidth of 40 nm, resulting in an axial resolution of approximately 7 μm in the eye and is used routinely worldwide. The High-Res OCT works with a central wavelength of 840 nm and an increased bandwidth of 130 nm, making it possible to improve the optical axial resolution in tissue from 7 to 3 µm, without increasing the maximum laser exposure limit. The improved axial resolution of the High-Res OCT results in clearer and more detailed images. The technique is routinely used in clinical practice and the device used for High-Res-OCT (Heidelberg, SPECTRALIS® High-Res OCT- DMR001) has received CE mark (european conformity in the extended Single Market in the European Economic Area) approval in March 2021. We plan to compare High-Res-OCT as an imaging modality to conventional imaging modalities used in clinical routine, such as the Spectral-Domain-OCT (SD-OCT) ;

Study Design

Related Conditions & MeSH terms

Diabetic Macular Edema
Diabetic Retinopathy
Edema
Glaucoma
Hypertensive Retinopathy
Macular Degeneration
Macular Disease
Macular Edema
Neovascularization, Pathologic
Optic Nerve Diseases
Papilledema
Retinal Artery Occlusion
Retinal Detachment
Retinal Disease
Retinal Diseases
Retinal Dystrophies
Retinal Dystrophy
Retinal Edema
Retinal Neovascularization
Retinal Vein Occlusion
Uveitis

Clinical Trial Details

NCT number	NCT05130385
Study type	Observational
Source	University Hospital Inselspital, Berne
Contact	Martin S Zinkernagel, MD, PhD
Phone	+41316329565
Email	martin.zinkernagel@insel.ch
Status	Recruiting
Phase
Start date	November 30, 2021
Completion date	November 30, 2023

View Details

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