Retinal Disease Clinical Trial
Official title:
Single Centre Study: Investigational Medical Device of Transscleral Optical Phase Imaging for Retinal Imaging in Healthy Eyes and Retinal Pathology.
Retinal diseases are the major cause of blindness in industrialized countries and while tremendous effort is made to develop novel therapeutic strategies to rescue retinal cells, optimal means to evaluate the effects of such treatments is still missing. Nowadays, diseases diagnosis and treatment monitoring are performed thanks to imaging devices and functional measurements (visual acuity of visual field tests). These eye examinations lead to the detection of large scale damages of the retinal tissue, i.e. the diagnosis is made too late or the treatments cannot be adapted in time. With the developed technology, the goal is to provide a tool to the ophthalmologists that allow for better treatment monitoring and early diagnosis. Indeed, the technology is able to image the retinal tissues with a ten times more detailed visualization as compared to the standard of care (OCT instruments, SLO instruments or eye fundus cameras). Towards this goal, we designed the present protocol in order to test the technology with a clinical prototype (Cellularis version 1) in a clinical environment. The objective is to describe and quantify at the cellular level the retina of patient affected by different retinal diseases as well as the healthy retina of people with different ages. We will assess the repeatability of the instrument and compare the results of the measurements with images obtained with the standard of care (OCT and SLO images).
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04956237 -
Retinal Surgery With or Without Anesthesiologist, Comparison of Surgeon and Patient's Comfort
|
||
| Recruiting |
NCT01432847 -
Cell Collection to Study Eye Diseases
|
||
| Active, not recruiting |
NCT04130841 -
Effects of Internal Limiting Membrane Peeling on Visual Function in Epiretinal Membrane Surgery
|
N/A | |
| Recruiting |
NCT03713268 -
Intraoperative OCT Guidance of Intraocular Surgery II
|
||
| Active, not recruiting |
NCT03872479 -
Single Ascending Dose Study in Participants With LCA10
|
Phase 1/Phase 2 | |
| Active, not recruiting |
NCT04636307 -
Characterization of Retinal Disease Progression in Eyes With Non Proliferative Diabetic Retinopathy in Diabetes Type 2 Using Non-invasive Procedures (CHART)
|
||
| Recruiting |
NCT02921568 -
Side-by-Side Comparison of P200TE and Spectral OCT/SLO on Diseased Eyes
|
N/A | |
| Completed |
NCT02315170 -
Assessment of Novel Intraocular Injection Guide
|
N/A | |
| Completed |
NCT00069199 -
Optical Coherence Tomography Comparative Study
|
N/A | |
| Withdrawn |
NCT03603990 -
Effect of Vitrectomy on the Evolution of Refractory Diabetic Macular Edema
|
N/A | |
| Active, not recruiting |
NCT04123626 -
A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene
|
Phase 1/Phase 2 | |
| Withdrawn |
NCT02445001 -
Erythrocyte Ghost Mediated Retinal Diagnosis
|
N/A | |
| Completed |
NCT01468337 -
Topical Interferon Gamma-1b for Central Serous Chorioretinopathy
|
Phase 1/Phase 2 | |
| Completed |
NCT01227993 -
Extension Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy
|
Phase 1/Phase 2 | |
| Completed |
NCT00792259 -
Topcon 3D OCT-1000 Optical Coherence Tomography System
|
||
| Completed |
NCT00035906 -
Research Study in Patients With Persistent Macular Edema
|
Phase 2 | |
| Recruiting |
NCT05158699 -
Effectiveness of Periocular Drug Injection in CATaract Surgery
|
Phase 3 | |
| Terminated |
NCT04110015 -
Assessment of Visual Function in Ophthalmic Disorders Using Virtual Visual Field Analysis
|
||
| Recruiting |
NCT03592017 -
Performance of Long-wavelength Autofluorescence Imaging
|
N/A | |
| Recruiting |
NCT03823092 -
Polarization Perception in Health and Disease. Testing a New Sight Test
|