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Retinal Detachment clinical trials

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NCT ID: NCT01845571 Recruiting - Clinical trials for Rhegmatogenous Retinal Detachment

Retinal Detachment - Demographic and Clinical Survey

Start date: October 2011
Phase:
Study type: Observational

Background: Rhegmatogenous retinal detachment is an ophthalmic emergency that, without surgical repair, often leads to blindness. The incidence is about 1/10000/year. The leading causes are myopia and aging which cause retinal tears often resulting in retinal detachment. Patients commonly experience photopsia, floaters, and peripheral visual field loss. Two different general surgical treatment options exist for retinal detachment; scleral buckling or vitrectomy. However, the precise indications for each approach have not been well established. Correct classification of the retinal detachment is important. The first step is to decide whether an intra- or extra-ocular surgical approach is more appropriate. Simple rhegmatogenous retinal detachments are usually treated extraocularly with scleral buckling surgery, whereas more complicated cases require intraocular primary pars plana vitrectomy and one or more of gas, silicone oil, laser therapy, or cryotherapy. Study objectives: The purpose of this study is to evaluate different surgical techniques for the treatment of retinal detachment. Data relating to retinal status before treatment, surgical treatment, post-operative anatomy and visual acuity, post-operative OCT, and intra- and post-operative complications will be collected. Vitreous cytokines will also be analyzed to monitor intravitreal inflammation as a result of retinal detachment.

NCT ID: NCT01793168 Recruiting - Clinical trials for Retinitis Pigmentosa

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS
Start date: July 2010
Phase:
Study type: Observational [Patient Registry]

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, individuals and researchers to help in the advancement of research in over 7,000 rare diseases. The registry is free for patients to enroll and researchers to access. Visit sanfordresearch.org/CoRDS to enroll.

NCT ID: NCT01604616 Recruiting - Retinal Detachment Clinical Trials

Short Term Postoperative Tamponade Using Perfluorocarbon Liquid for Giant Retinal Tears

Start date: January 1998
Phase: N/A
Study type: Observational

The purpose of the article is, to investigate the efficacy and safety of perfluorocarbon liquid (PFCL) ,as a short term postoperative tamponade for treating retinal detachment ,associated with giant retinal tears.

NCT ID: NCT01417572 Recruiting - Retinal Detachment Clinical Trials

Adjunctive Local Application of Lidocaine During Scleral Buckling Under General Anesthesia

Start date: January 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effect of topical lidocaine in scleral buckling surgery.

NCT ID: NCT01297816 Recruiting - Retinal Detachment Clinical Trials

Evaluation of Neuroprotective Effect of Minocycline

minocyclin &RD
Start date: December 2010
Phase: Phase 2
Study type: Interventional

This process appears as a incredible and progressive event that will not stop till reattachment of RPE and neurosensory retina happened . Process of degeneration begins from first hours of RD (Retinal Detachment) establishment Neuroprotection of photoreceptor following RD is a novel and debatable discussion encountered in recent years . How to stop this phenomena and neuroprotective agent role in this issue are a new interest of researcher. In the study the investigators are planning to perform a clinical trial to demonstrate the minocycline neuroprotective effect in a double blind design as this impact has been implicated previously in a animal study

NCT ID: NCT01261533 Recruiting - Retinal Detachment Clinical Trials

Flexibility, Efficacy, and Safety of a Foldable Capsular Vitreous Body in the Treatment of Severe Retinal Detachment

Start date: September 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the feasibility, primary safety and efficacy of foldable capsular vitreous body (FCVB) in the treatment of retinal detachment, based on the multi-center clinical trial.

NCT ID: NCT00370279 Recruiting - Clinical trials for Pseudophakic Retinal Detachment

Surgical Management of Pseudophakic and Aphakic Retinal Detachment; a Randomized Clinical Trial

Start date: September 2005
Phase: Phase 3
Study type: Interventional

To compare the visual and anatomical outcomes and complications of four surgical techniques (1- scleral buckling, 2- primary vitrectomy without encircling band, 3- primary vitrectomy with encircling band, 4- triamcinolone assisted vitrectomy) for management of pseudophakic and aphakic retinal detachment