Effect of Systemic Hypoxia and Hyperoxia on Retinal Oxygen Saturation

Retinal Blood Flow Clinical Trial

Official title:
Effect of Systemic Hypoxia and Hyperoxia on Retinal Oxygen Saturation

Status Completed

Clinical Trial Summary

Adequate perfusion and oxygenation is essential for the function of the inner retina. Although it is known that oxygen tension is very well autoregulated in the retina, the physiological mechanisms behind this regulation process are not fully explored. The development of new instruments for the non-invasive measurement of oxygen tension in retinal vessels now allows for the more precise investigation of these physiological processes. The current study seeks to evaluate the retinal oxygen saturation in healthy subjects while breathing different oxygen mixtures to achieve a hypoxic and a hyperoxic state.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01692821
Study type	Interventional
Source	Medical University of Vienna
Contact
Status	Completed
Phase	Phase 4
Start date	June 2012
Completion date	January 2013

View Details

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