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RET Gene Mutation clinical trials

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NCT ID: NCT06109558 Recruiting - Clinical trials for Non Small Cell Lung Cancer

The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC

PROFILE
Start date: December 31, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is an open-label, single-arm, dose-escalation, multicenter phase I/II clinical trial. The primary endpoints of this study were to evaluated the safety, tolerability, pharmacokinetic profile and preliminary efficacy of HE003 in combination with osimertinib in patients with advanced solid tumors who have failed previous standard therapy. The secondary endpoints of this study were to evaluated the efficacy HE003 in combination with osimertinib in patients with advanced solid tumors who have failed previous standard therapy.