Impact of Fluid Resuscitation Protocol on the Incidence of Reoperation for Bleeding After Emergency Cardiopulmonary Bypass Grafting

Resternotomy Clinical Trial

— Volu-CABG  

Official title:

Impact of Fluid Resuscitation Protocol on the Incidence of Reoperation for Bleeding After Emergency Cardiopulmonary Bypass Grafting

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT04533698
• Other study ID #: 2020-01833
• Status: Active, not recruiting
• Start date: January 1, 2009
• Est. completion date: June 30, 2024

Study information

• Verified date: June 2023
• Source: University Hospital, Basel, Switzerland
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This is a retrospective data analysis of patients that underwent elective or emergency cardiopulmonary bypass. Resternotomy due to bleeding is frequent after sternotomy. Also due to implementation of Argipressin into clinical practice fluid resuscitation protocol has changed to more vasopressors and less fluid within the past five years. The investigators want to explore the influence of volume resuscitation protocol on incidence of rethoracotomy during the past twenty years.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 3000
• Est. completion date: June 30, 2024
• Est. primary completion date: May 31, 2021
• Gender: All
• Age group: 18 Years to 99 Years

Eligibility

Inclusion Criteria:

• All patients that underwent elective or emergency aortocoronary bypass at the University Hospital Basel between 2009 and 2020.

Exclusion Criteria:

• None.

Related Conditions & MeSH terms

• Emergencies
• Resternotomy

Intervention

Other:
• Assessment of reason for resternotomy
No intervention is performed. Reasons for resternotomy (coagulation, fluid balance and other) are retrospectively assessed.
• Assessment of reason for avoidance of resternotomy
No intervention is performed. Reasons for avoidance resternotomy (coagulation, fluid balance and other) are retrospectively assessed.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Basel, Switzerland

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Resternotomy	Resternotomy yes or no after elective or emergency aortocoronary bypass	7 days